Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20080451 | 0.83 | TSHR (0.45) | ALDH1A1TSHRTDP1SMN1; SMN2TP53 | |
| SCHEMBL12017369 | 0.83 | TSHR (0.45) | ALDH1A1TSHRTDP1SMN1; SMN2TP53 | |
| SCHEMBL23509547 | 0.83 | TSHR (0.45) | ALDH1A1TSHRTDP1SMN1; SMN2TP53 | |
| SCHEMBL278333 | 0.81 | ALDH1A1 (0.61) | ALDH1A1TSHRTDP1SMN1; SMN2TP53 | |
| SCHEMBL13238227 | 0.79 | ALDH1A1 (0.36) | ALDH1A1TSHRTP53MDM2MAPT | |
| SCHEMBL24440752 | 0.78 | MAPT (0.40) | ALDH1A1TDP1SMN1; SMN2GAACYP3A4 | |
| SCHEMBL12017373 | 0.78 | TSHR (0.41) | ALDH1A1TSHRTDP1SMN1; SMN2TP53 | |
| SCHEMBL17693406 | 0.78 | ALDH1A1 (0.57) | ALDH1A1TSHRTDP1SMN1; SMN2TP53 | |
| SCHEMBL16715946 | 0.76 | SMN1; SMN2 (0.42) | ALDH1A1TSHRTDP1SMN1; SMN2TP53 | |
| SCHEMBL16715745 | 0.76 | TSHR (0.42) | ALDH1A1TSHRTDP1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754823-B2 | Vegetable based dioxanone derivatives, synthesis and uses thereof | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2010-07-13 | — | — | US | disclosed |
| US-7754823-B2 | Vegetable based dioxanone derivatives, synthesis and uses thereof | ARCHER-DANIELS-MIDLAND COMPANY (US) | 2010-07-13 | — | — | US | disclosed |
| US-5011918-A | Siloxane Derivatives Are Useful In Glass Fiber Sizing Compositions | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-4929670-A | GLASS SIZING COMPOSITIONS | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1990-05-29 | — | — | US | disclosed |
| US-4839449-A | SIZING COMPOSITION FOR GLASS | NATIONAL STARCH AND CHEMICAL CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0314063-A2 | Polysaccharides containing aromatic aldehydes and their derivatization via amine-aldehyde interactions | National Starch and Chemical Corporation (US) | 1989-05-03 | — | — | EP | disclosed |