Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19334491 | 0.83 | SIGMAR1 (0.58) | SIGMAR1ATMTAAR1OPRK1NPC1 | |
| SCHEMBL18435350 | 0.82 | SIGMAR1 (0.72) | SIGMAR1ATMTAAR1OPRK1SMN1; SMN2 | |
| SCHEMBL7284929 | 0.80 | SIGMAR1 (0.55) | SIGMAR1ATMTAAR1OPRK1NPC1 | |
| SCHEMBL10939197 | 0.80 | SIGMAR1 (0.55) | SIGMAR1ATMTAAR1OPRK1NPC1 | |
| SCHEMBL9150896 | 0.79 | SIGMAR1 (0.62) | SIGMAR1ATMTAAR1 | |
| SCHEMBL22207039 | 0.78 | SIGMAR1 (0.55) | SIGMAR1CYP3A4IDO1SMN1; SMN2POLB | |
| SCHEMBL1148376 | 0.78 | SIGMAR1 (0.68) | SIGMAR1ATMTAAR1OPRK1NPC1 | |
| SCHEMBL27849653 | 0.76 | POLB (0.53) | SIGMAR1ATMTAAR1OPRK1NPC1 | |
| SCHEMBL24457722 | 0.75 | SIGMAR1 (0.63) | SIGMAR1ATMTAAR1OPRK1NPC1 | |
| SCHEMBL7605629 | 0.75 | SIGMAR1 (0.63) | SIGMAR1ATMTAAR1OPRK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021187-A | In aqueous solutions iwth peroxy compounds; antisoilants; hydrophobic stains | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1991-06-04 | — | — | US | disclosed |