Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.63 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11362361 | 0.98 | SIGMAR1 (0.61) | SIGMAR1ATMTAAR1OPRK1TSHR | |
| SCHEMBL1148376 | 0.83 | SIGMAR1 (0.68) | SIGMAR1ATMTAAR1OPRK1TSHR | |
| SCHEMBL4412493 | 0.79 | SIGMAR1 (0.63) | SIGMAR1ATMTAAR1OPRK1TSHR | |
| SCHEMBL6716515 | 0.79 | SIGMAR1 (0.63) | SIGMAR1ATMTAAR1OPRK1TSHR | |
| SCHEMBL10725926 | 0.79 | SIGMAR1 (0.63) | SIGMAR1ATMTAAR1OPRK1TSHR | |
| SCHEMBL24457722 | 0.79 | SIGMAR1 (0.63) | SIGMAR1ATMTAAR1OPRK1TSHR | |
| SCHEMBL9360922 | 0.78 | SIGMAR1 (1.00) | SIGMAR1OPRK1HTR1ASLC6A2ADRA1A | |
| SCHEMBL19498803 | 0.78 | OPRK1 (0.81) | SIGMAR1OPRK1TSHRALDH1A1LMNA | |
| SCHEMBL18435350 | 0.78 | SIGMAR1 (0.72) | SIGMAR1ATMTAAR1OPRK1SMN1; SMN2 | |
| SCHEMBL12269593 | 0.78 | CYP3A4 (0.63) | SIGMAR1ATMTAAR1OPRK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973725-B1 | NEW 1,7,7-TRIMETHYL-BICYCLO 2.2.1]HEPTANE DERIVATIVES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2002-06-19 | — | — | EP | disclosed |
| US-6093747-A | SELECTIVELY BINDING 5-HT2C RECEPTORS IN A MAMMAL | EGIS GYOGYSZERGYAR RT. (HU) | 2000-07-25 | — | — | US | disclosed |
| EP-0973725-A2 | NEW 1,7,7-TRIMETHYL-BICYCLO 2.2.1]HEPTANE DERIVATIVES | EGIS GYOGYSZERGYAR RT. (HU) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998017230-A2 | NEW 1,7,7-TRIMETHYL-BICYCLO[2.2.1]HEPTANE DERIVATIVES | EGIS Gyógyszergyár Rt. (HU) | 1998-04-30 | — | — | WO | disclosed |