Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768782 | 1.00 | USP2 (0.57) | USP2G6PC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3489173 | 0.80 | USP2 (0.53) | USP2G6PC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9769017 | 0.80 | G6PC1 (0.56) | USP2G6PC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3489176 | 0.80 | USP2 (0.53) | USP2G6PC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9769019 | 0.80 | G6PC1 (0.56) | USP2G6PC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14517008 | 0.79 | USP2 (0.62) | USP2G6PC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22862043 | 0.79 | USP2 (0.62) | USP2G6PC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11637392 | 0.78 | USP2 (0.57) | USP2G6PC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3943694 | 0.77 | USP2 (0.70) | USP2G6PC1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3943697 | 0.77 | USP2 (0.70) | USP2G6PC1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023334-A | Anthelmintic pyridinyl acylhydrazones | THE UPJOHN COMPANY (US) | 1991-06-11 | — | — | US | claimed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | claimed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | claimed |
| US-5011932-A | Anthelmintic pyridinyl acylhydrazones derivatives | UPJOHN COMPANY (US) | 1991-04-30 | — | — | US | disclosed |