SCHEMBL3943697

SCHEMBL3943697

CN(N=Cc1ccccn1)c1ccccc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.70
G6PC1 P35575 1/20 0.55
MAOA P21397 2/20 0.54
MAOB P27338 1/20 0.54
NR4A1 P22736 1/20 0.49
MEN1 O00255 9/20 0.46
KMT2A Q03164 9/20 0.46
NPC1 O15118 7/20 0.46
RAB9A P51151 7/20 0.46
MAPT P10636 6/20 0.46
SMN1; SMN2 Q16637 5/20 0.46
HPGD P15428 1/20 0.46
TDP1 Q9NUW8 3/20 0.45
ATM Q13315 1/20 0.45
ALDH1A1 P00352 3/20 0.45
ALOX12 P18054 1/20 0.45
LMNA P02545 2/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3943694 1.00 USP2 (0.70) USP2G6PC1MAOAMAOBNR4A1
SCHEMBL6711619 0.83 USP2 (0.56) USP2G6PC1MAOAMAOBNR4A1
SCHEMBL6711615 0.83 USP2 (0.56) USP2G6PC1MAOAMAOBNR4A1
SCHEMBL14517008 0.82 USP2 (0.62) USP2G6PC1MAOAMAOBNR4A1
SCHEMBL22862043 0.82 USP2 (0.62) USP2G6PC1MAOAMAOBNR4A1
SCHEMBL11637392 0.77 USP2 (0.57) USP2G6PC1MAOAMAOBNR4A1
SCHEMBL9768782 0.77 USP2 (0.57) USP2G6PC1MAOAMAOBNR4A1
SCHEMBL9768784 0.77 USP2 (0.57) USP2G6PC1MAOAMAOBNR4A1
SCHEMBL11286746 0.74 G6PC1 (0.70) USP2G6PC1MAOAMAOBNR4A1
SCHEMBL1131506 0.74 MAPT (0.56) G6PC1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105272793-B Method for synthesizing aryl hydrazone 南京理工大学 2017-02-15 CN disclosed
CN-105272793-A Method for synthesizing aryl hydrazone UNIV NANJING SCIENCE & TECH 2016-01-27 CN disclosed
EP-1847250-B1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes PROCTER & GAMBLE (US) 2009-12-23 EP disclosed
CN-101426471-A Agents for colouring keratin fibres comprising zwitterionic azomethine dyes WELLA AG (US) 2009-05-06 CN disclosed
US-7513918-B2 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes THE PROCTER & GAMBLE COMPANY (US) 2009-04-07 US disclosed
EP-1852104-A1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes Wella Aktiengesellschaft (DE) 2007-11-07 EP disclosed
WO-2007119228-A2 AGENTS FOR COLOURING KERATIN FIBRES COMPRISING ZWITTERIONIC AZOMETHINE DYES THE PROCTER & GAMBLE COMPANY (US) 2007-10-25 WO disclosed
US-20070245501-A1 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes WELLA OPERATIONS US, LLC 2007-10-25 US disclosed
EP-1847250-A1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes Wella Aktiengesellschaft (DE) 2007-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070245501-A1 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes KRT18, IK, RARG USP2 2968/4885G6PC1 4611/4885MAOA 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.