Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10592352 | 0.81 | HCAR2 (0.53) | CTSDKMT2AKDM4EALDH1A1HTT | |
| SCHEMBL3823522 | 0.81 | ESR1 (0.46) | CTSDESR1ESR2CRHBPCRHR2 | |
| SCHEMBL28752431 | 0.78 | ESR1 (0.59) | ESR1ESR2CRHBPCRHR2KMT2A | |
| SCHEMBL3990914 | 0.78 | ESR1 (0.59) | ESR1ESR2CRHBPCRHR2KMT2A | |
| SCHEMBL9118007 | 0.78 | CTSD (0.46) | CTSDKMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL6635452 | 0.77 | ESR1 (0.50) | ESR1ESR2CRHBPCRHR2KMT2A | |
| SCHEMBL1955 | 0.77 | ESR1 (0.53) | CTSDESR1ESR2CRHBPCRHR2 | |
| SCHEMBL11000173 | 0.77 | KMT2A (0.57) | ESR1ESR2CRHBPCRHR2KMT2A | |
| SCHEMBL10966117 | 0.77 | ESR1 (0.42) | ESR1ESR2CRHBPCRHR2LMNA | |
| SCHEMBL27752446 | 0.77 | ALDH1A1 (0.63) | CTSDKMT2ALMNAALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2691452-B1 | CURABLE FLUOROELASTOMER COMPOSITION | DU PONT (US) | 2018-11-28 | — | — | EP | claimed |
| US-8816013-B2 | Curable fluoroelastomer composition | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-26 | — | — | US | claimed |
| EP-2691452-A1 | CURABLE FLUOROELASTOMER COMPOSITION | E.I. Du Pont De Nemours And Company (US) | 2014-02-05 | — | — | EP | claimed |
| US-20130072643-A1 | CURABLE FLUOROELASTOMER COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-03-21 | — | — | US | claimed |
| WO-2012135782-A1 | CURABLE FLUOROELASTOMER COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-04 | — | — | WO | claimed |
| CN-110003215-A | It can be used for treating pyrrolo- [1,2-f] [1,2,4] triazine of respiratory syncytial virus infection | 吉利德科学公司 | 2019-07-12 | — | — | CN | disclosed |
| CN-109563509-A | Target the delivering nucleic acid compound certainly of the reduction size of long non-coding RNA | 阿克赛医药公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-105899216-B | Pyrrolo [1,2-f ] [1,2,4] triazines useful for the treatment of respiratory syncytial virus infection | 吉利德科学公司 | 2019-03-05 | — | — | CN | disclosed |
| EP-2691452-B1 | CURABLE FLUOROELASTOMER COMPOSITION | DU PONT (US) | 2018-11-28 | — | — | EP | disclosed |
| CN-108135923-A | Target superoxide dismutase 1（SOD1）Nucleic acid molecules | 阿克赛医药公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-104487485-B | polycarbonate polyol composition and method | 沙特阿美技术公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107847763-A | Targeted selection of patients eligible for treatment with cortistatin derivatives | 哈佛学院院长等 | 2018-03-27 | — | — | CN | disclosed |
| US-20130072643-A1 | CURABLE FLUOROELASTOMER COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2012135782-A1 | CURABLE FLUOROELASTOMER COMPOSITION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-10-04 | — | — | WO | disclosed |
| US-5023334-A | Anthelmintic pyridinyl acylhydrazones | THE UPJOHN COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| US-5011932-A | Anthelmintic pyridinyl acylhydrazones derivatives | UPJOHN COMPANY (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0214158-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
| WO-1986004582-A1 | ANTHELMINTIC PYRIDINYL ACYLHYDRAZONES, METHOD OF USE AND COMPOSITIONS | THE UPJOHN COMPANY (US) | 1986-08-14 | — | — | WO | disclosed |
| US-4111923-A | LUTEINIZING HORMONE RELEASING FACTOR ANTAGONISTS | PARKE, DAVIS & COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4086219-A | LUTEINIZING HORMONE RELEASING FACTOR ANTAGONISTS | PARKE, DAVIS & COMPANY (US) | 1978-04-25 | — | — | US | disclosed |