Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.49 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641387 | 0.92 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1HTTCTSL | |
| SCHEMBL10081124 | 0.84 | LMNA (0.63) | LMNASMN1; SMN2ALDH1A1HTTCTSL | |
| SCHEMBL10429420 | 0.83 | LMNA (0.58) | LMNASMN1; SMN2ALDH1A1HTTCTSL | |
| SCHEMBL13644307 | 0.83 | LMNA (0.58) | LMNASMN1; SMN2ALDH1A1HTTCTSL | |
| Glycine SCHEMBL8366779 | 0.83 | HTT (0.59) | LMNASMN1; SMN2ALDH1A1HTTCTSL | |
| SCHEMBL2065470 | 0.81 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2ALDH1A1HTTCTSL | |
| SCHEMBL10429418 | 0.80 | LMNA (0.58) | LMNASMN1; SMN2ALDH1A1HTTCTSL | |
| SCHEMBL3361808 | 0.80 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1HTTCTSL | |
| SCHEMBL2820683 | 0.80 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1HTTCTSL | |
| SCHEMBL5485588 | 0.80 | LMNA (0.61) | LMNASMN1; SMN2ALDH1A1HTTCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |