Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.51 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2820683 | 1.00 | LMNA (0.61) | LMNASMN1; SMN2HTTPLAUALDH1A1 | |
| Acetic Acid SCHEMBL8324881 | 0.95 | LMNA (0.56) | LMNASMN1; SMN2HTTPLAUALDH1A1 | |
| SCHEMBL8156969 | 0.94 | ALDH1A1 (0.58) | LMNASMN1; SMN2HTTPLAUALDH1A1 | |
| SCHEMBL16258192 | 0.94 | ALDH1A1 (0.58) | LMNASMN1; SMN2HTTPLAUALDH1A1 | |
| SCHEMBL3254019 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2HTTPLAUALDH1A1 | |
| SCHEMBL22580054 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2HTTPLAUALDH1A1 | |
| SCHEMBL21771638 | 0.87 | LMNA (0.62) | LMNASMN1; SMN2HTTPLAUALDH1A1 | |
| SCHEMBL1337448 | 0.87 | LMNA (0.58) | LMNASMN1; SMN2HTTPLAUALDH1A1 | |
| SCHEMBL11783251 | 0.86 | HTT (0.66) | LMNASMN1; SMN2HTTPLAUALDH1A1 | |
| SCHEMBL6741072 | 0.86 | LMNA (0.65) | LMNASMN1; SMN2HTTALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056446-A1 | ANTICONVULSANT DRUGS AND PHARMACEUTICAL COMPOSITIONS THEREOF | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-12-06 | — | — | EP | claimed |
| US-6028102-A | Anticonvulsant drugs and pharmaceutical compositions thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM | 2000-02-22 | — | — | US | claimed |
| WO-1999043309-A2 | ANTICONVULSANT DRUGS AND PHARMACEUTICAL COMPOSITIONS THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY (IL) | 1999-09-02 | — | — | WO | claimed |
| EP-2210598-B1 | Anticonvulsant amino acids for the treatment of pain | RES CORP TECHNOLOGIES INC (US) | 2013-09-18 | — | — | EP | disclosed |
| EP-1486205-B1 | Use of anticonvulsant aminoacids for the treatment of migraine | RES CORP TECHNOLOGIES INC (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1486206-B1 | Uses of anticonvulsant aminoacids for the treatment of bipolar disorders | RES CORP TECHNOLOGIES INC (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1365787-B1 | USE OF AMINO ACID ANTICONVULSANTS FOR TREATMENT OF PAIN | RES CORP TECHNOLOGIES INC (US) | 2007-03-21 | — | — | EP | disclosed |
| EP-1056446-A1 | ANTICONVULSANT DRUGS AND PHARMACEUTICAL COMPOSITIONS THEREOF | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-12-06 | — | — | EP | disclosed |
| EP-1056446-A1 | ANTICONVULSANT DRUGS AND PHARMACEUTICAL COMPOSITIONS THEREOF | YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2000-12-06 | — | — | EP | disclosed |
| US-6028102-A | Anticonvulsant drugs and pharmaceutical compositions thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM | 2000-02-22 | — | — | US | disclosed |
| US-6028102-A | Anticonvulsant drugs and pharmaceutical compositions thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM | 2000-02-22 | — | — | US | disclosed |
| WO-1999043309-A3 | ANTICONVULSANT DRUGS AND PHARMACEUTICAL COMPOSITIONS THEREOF | YISSUM RES DEV CO (IL) | 2000-01-13 | — | — | WO | disclosed |
| WO-1999043309-A2 | ANTICONVULSANT DRUGS AND PHARMACEUTICAL COMPOSITIONS THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY (IL) | 1999-09-02 | — | — | WO | disclosed |
| WO-1999043309-A2 | ANTICONVULSANT DRUGS AND PHARMACEUTICAL COMPOSITIONS THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY (IL) | 1999-09-02 | — | — | WO | disclosed |