Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 16/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976898 | 1.00 | ALOX5AP (0.45) | ALOX5APKDM4EHSD17B10NPC1RAB9A | |
| SCHEMBL977277 | 0.82 | ALOX5AP (0.45) | ALOX5AP | |
| SCHEMBL12920623 | 0.82 | ALOX5AP (0.57) | ALOX5APKDM4EHSD17B10 | |
| SCHEMBL974436 | 0.82 | ALOX5AP (0.57) | ALOX5APKDM4EHSD17B10 | |
| SCHEMBL974480 | 0.81 | ALOX5AP (0.45) | ALOX5APKDM4EHSD17B10NOTUM | |
| SCHEMBL974481 | 0.81 | ALOX5AP (0.45) | ALOX5APKDM4EHSD17B10NOTUM | |
| SCHEMBL977781 | 0.81 | ALOX5AP (0.54) | ALOX5APKDM4EHSD17B10 | |
| SCHEMBL977780 | 0.81 | ALOX5AP (0.54) | ALOX5APKDM4EHSD17B10 | |
| SCHEMBL975772 | 0.80 | ALOX5AP (0.45) | ALOX5APKDM4EHSD17B10 | |
| SCHEMBL975771 | 0.80 | ALOX5AP (0.45) | ALOX5APKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | MERCK & CO., INC. | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003815-A1 | DIPHENYL SUBSTITUTED CYCLOALKANES | PTGIS, PTGS1, LTC4S | ALOX5AP 47/4885KDM4E 3639/4885HSD17B10 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.