Fluoride

Fluoride

SCHEMBL9769028

C=C(CCCN)C(=O)OC(C)(C)C.F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.37
HDAC1 Q13547 2/20 0.35
HDAC2 Q92769 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
GABRR3 A8MPY1 1/20 0.35
GABRP O00591 1/20 0.35
GABRD O14764 1/20 0.35
HDAC3 O15379 1/20 0.35
GABBR2 O75899 1/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
GABRA1 P14867 1/20 0.35
TSHR P16473 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35
GABRR1 P24046 1/20 0.35
GABRB3 P28472 1/20 0.35
GABRR2 P28476 1/20 0.35
SLC6A1 P30531 1/20 0.35
GABRA5 P31644 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL140339 0.98 CYP1A2 (0.38) CYP1A2HDAC1HDAC2HDAC6GABRR3
SCHEMBL18094238 0.93 PAOX (0.41) CYP1A2HDAC1HDAC2HDAC6GABRR3
SCHEMBL9540623 0.86 DGAT1 (0.30)
SCHEMBL21981517 0.81 CES1 (0.39) TSHR
SCHEMBL9644895 0.79 EPHX2 (0.41) HDAC1HDAC2HDAC6HDAC3TSHR
SCHEMBL787672 0.79 CES2 (0.41) TSHRKMT2AHDAC11
SCHEMBL18007131 0.79 SLC22A6 (0.42) LMNATSHRKMT2AHDAC11NFKB1
Methacrylic Acid SCHEMBL25426815 0.79 TET2 (0.32)
SCHEMBL2539200 0.79 CYP1A2 (0.41) CYP1A2HDAC1HDAC2HDAC6GABRR3
SCHEMBL28279994 0.78 DGAT1 (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5037638-A Anticaries agent BISCO INC. (US) 1991-08-06 US claimed