Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3465282 | 0.82 | ALDH1A1 (0.37) | ALDH1A1KDM4ETDP1 | |
| SCHEMBL1756488 | 0.80 | KDM4E (0.40) | ALDH1A1KDM4ETDP1LMNAESR1 | |
| SCHEMBL3076471 | 0.80 | KDM4E (0.40) | ALDH1A1KDM4ETDP1LMNAESR1 | |
| SCHEMBL6609452 | 0.80 | GSK3B (0.36) | ALDH1A1KDM4ETDP1LMNAPRNP | |
| SCHEMBL20122066 | 0.80 | KDM4E (0.40) | ALDH1A1KDM4ETDP1LMNAESR1 | |
| SCHEMBL15791269 | 0.80 | KDM4E (0.40) | ALDH1A1KDM4ETDP1LMNAESR1 | |
| SCHEMBL3883593 | 0.80 | KDM4E (0.40) | ALDH1A1KDM4ETDP1LMNAESR1 | |
| SCHEMBL3877421 | 0.80 | KDM4E (0.40) | ALDH1A1KDM4ETDP1LMNAESR1 | |
| SCHEMBL1414863 | 0.78 | KDM4E (0.45) | ALDH1A1KDM4ETDP1RXFP1 | |
| SCHEMBL3357183 | 0.78 | TDP1 (0.41) | ALDH1A1KDM4ETDP1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-1031536-A | 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application | OTSUKA PHARMA CO LTD (JP) | 1989-03-08 | — | — | CN | disclosed |