Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3824962 | 0.79 | — | — | |
| SCHEMBL14964648 | 0.76 | CA1 (0.33) | CA1CA2CA9CA7 | |
| SCHEMBL9769073 | 0.76 | CA1 (0.55) | CA1CA2CA9CA7 | |
| SCHEMBL12113817 | 0.75 | TSHR (0.44) | CA1CA2CA9CA7 | |
| SCHEMBL12113819 | 0.75 | TSHR (0.33) | CA1CA2CA9CA7 | |
| SCHEMBL9301160 | 0.71 | ALDH1A1 (0.35) | — | |
| SCHEMBL10375704 | 0.71 | — | — | |
| SCHEMBL31643142 | 0.69 | USP2 (0.44) | — | |
| SCHEMBL20483122 | 0.69 | — | — | |
| SCHEMBL28548531 | 0.69 | CA1 (0.46) | CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62195389-A | — | — | None | — | — | JP | disclosed |
| US-20170088564-A1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | DSM IP ASSETS B.V. (NL) | 2017-03-30 | — | — | US | disclosed |
| US-20170088564-A1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | DSM IP ASSETS B.V. (NL) | 2017-03-30 | — | — | US | disclosed |
| US-20140135408-A1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | DSM IP ASSETS B.V. (NL) | 2014-05-15 | — | — | US | disclosed |
| US-20140135408-A1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | DSM IP ASSETS B.V. (NL) | 2014-05-15 | — | — | US | disclosed |
| US-5047491-A | Molding materials; waterproofing, oil repellents, antifouling agents | CHISSO CORPORATION (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0355497-A2 | Polyorganosiloxane compounds | Chisso Corporation (JP) | 1990-02-28 | — | — | EP | disclosed |
| JP-S62195389-A | HYDROXYL GROUP-CONTAINING SILOXANE COMPOUND | CHISSO CORP | 1987-08-28 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170088564-A1 | SILICONE CONTAINING MONOMERS WITH HYDROPHILIC END GROUPS | HRH3, HRH1, H1-3 | CA1 2152/4885CA2 3440/4885CA9 3703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.