SCHEMBL9301160

SCHEMBL9301160

C=CCCCCC(CO[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
USP2 O75604 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20477537 0.77 LMNA (0.33) TSHR
SCHEMBL28446709 0.76 ALDH1A1 (0.35) ALDH1A1USP2CYP3A4MAPTHPGD
SCHEMBL18175821 0.76 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL9769079 0.71 CA1 (0.37)
SCHEMBL20482721 0.71
SCHEMBL449903 0.69 TBXAS1 (0.34)
SCHEMBL4453485 0.69 TSHR (0.42) ALDH1A1MAPTTSHR
SCHEMBL18533162 0.69 TSHR (0.42) ALDH1A1USP2CYP3A4MAPTHPGD
SCHEMBL7164245 0.68
SCHEMBL4462375 0.67 TSHR (0.46) ALDH1A1USP2CYP3A4MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5367090-A Unsaturated silane monomers ARISTECH CHEMICAL CORPORATION (US) 1994-11-22 US claimed
US-5373061-A Polyolefins having active groups on its backbone ARISTECH CHEMICAL CORPORATION (US) 1994-12-13 US disclosed
US-5367090-A Unsaturated silane monomers ARISTECH CHEMICAL CORPORATION (US) 1994-11-22 US disclosed
US-5329037-A Olefin monomers containing a protective alkyl silane group ARISTECH CHEMICAL CORPORATION (US) 1994-07-12 US disclosed
US-5296562-A Ziegler-Natta catalytic addition polymerization of olefin and unsaturated silanol derivatives ARISTECH CHEMICAL CORPORATION (US) 1994-03-22 US disclosed
US-5296626-A Monomers for polymers containing silanol groups with unsaturated groups ARISTECH CHEMICAL CORPORATION (US) 1994-03-22 US disclosed
US-5294679-A Polymerization of an alpha olefin and an unsaturated silyl compound using a coordination catalyst of titanium chloride on a magnesium chloride support followed by hydroysis or alcoholyzing ARISTECH CHEMICAL CORPORATION (US) 1994-03-15 US disclosed