SCHEMBL9769190

SCHEMBL9769190

[CH2]CCCCCc1csc(C)c1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 4/20 0.33
POLB P06746 1/20 0.32
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
DAO P14920 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3534224 0.84
SCHEMBL2607172 0.82 PTGS2 (0.47) TP53
SCHEMBL19304397 0.82 PTGS2 (0.47) TP53
SCHEMBL10587640 0.82 PTGS2 (0.47) TP53
SCHEMBL18382236 0.82 PTGS2 (0.47) TP53
SCHEMBL15396902 0.82 PTGS2 (0.47) TP53
SCHEMBL23110802 0.81 DAO (0.34) LTB4RPOLBTP53MAPTDAO
SCHEMBL9769261 0.80 PTGS2 (0.45) TP53
SCHEMBL14365850 0.78 LTB4R (0.34) LTB4RPOLBDAO
SCHEMBL1637851 0.78 HPGD (0.45) POLBTP53MAPTDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4992534-A Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-02-12 US disclosed
CN-1031536-A 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application OTSUKA PHARMA CO LTD (JP) 1989-03-08 CN disclosed
EP-0303269-A2 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-02-15 EP disclosed