Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861006 | 0.81 | TSHR (0.42) | DPP4DPP8DPP9PREP | |
| SCHEMBL12787401 | 0.77 | GAA (0.42) | DPP4DPP8DPP9RAB9AFAP | |
| SCHEMBL2355780 | 0.77 | HSD17B10 (0.49) | — | |
| SCHEMBL7855614 | 0.77 | HSD17B10 (0.49) | — | |
| SCHEMBL5171011 | 0.77 | HSD17B10 (0.49) | — | |
| SCHEMBL7312802 | 0.75 | DPP4 (0.73) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL9840411 | 0.75 | DPP4 (0.73) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL18211214 | 0.75 | RAB9A (0.65) | RAB9A | |
| SCHEMBL8272734 | 0.75 | RAB9A (0.65) | RAB9A | |
| SCHEMBL7312806 | 0.75 | DPP4 (0.73) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| CN-1031536-A | 2 '-'-Deoxy-5-fluorouridine derivatives and its production and application | OTSUKA PHARMA CO LTD (JP) | 1989-03-08 | — | — | CN | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |