SCHEMBL9769248

SCHEMBL9769248

O=c1nc(C(Br)(Br)Br)[nH]c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.45
ALDH1A1 P00352 8/20 0.45
GAA P10253 3/20 0.45
LMNA P02545 2/20 0.45
HPGD P15428 2/20 0.45
GLA P06280 1/20 0.45
HTT P42858 1/20 0.45
ATM Q13315 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MAPT P10636 3/20 0.45
NPSR1 Q6W5P4 2/20 0.45
HSD17B10 Q99714 4/20 0.42
PARP1 P09874 4/20 0.42
CYP1A2 P05177 3/20 0.42
GPR3 P46089 2/20 0.42
TNKS2 Q9H2K2 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
TNKS O95271 1/20 0.42
BLM P54132 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10779485 0.84 ALDH1A1 (0.44) KDM4EALDH1A1GAALMNAHPGD
SCHEMBL9769434 0.84 MEN1 (0.49) KDM4EALDH1A1GAALMNAHPGD
SCHEMBL8646269 0.84 KDM4E (0.65) KDM4EALDH1A1GAALMNAHPGD
SCHEMBL30466799 0.84 KDM4E (0.65) KDM4EALDH1A1GAALMNAHPGD
SCHEMBL24413229 0.78 CHRNB2 (0.43) KDM4EALDH1A1GAALMNAHPGD
SCHEMBL9176920 0.78 KDM4E (0.46) KDM4EALDH1A1GAALMNAHPGD
SCHEMBL6887071 0.76 ALDH1A1 (0.52) KDM4EALDH1A1GAALMNAHPGD
SCHEMBL577953 0.75 NPC1 (0.52) KDM4EALDH1A1GAALMNAHPGD
SCHEMBL30014118 0.75 NPC1 (0.52) KDM4EALDH1A1GAALMNAHPGD
SCHEMBL103993 0.73 ALDH1A1 (0.53) KDM4EALDH1A1GAALMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5030548-A Photoiniator system comprising a 4,4'-bis(dialkylamino) benzophenone, an aromatic ketone and lophine dimer; also present a halogen compound leuco and dye; lithography; printing plates; photoresists FUJI PHOTO FILM CO., LTD. (JP) 1991-07-09 US disclosed
US-4584260-A 4,41-BIS(DIALKYLAMINO)BENZOPHENONE A BENZOPHENONE, 1,3,4-OXADIAZOLE COMPOUND, AROMATIC HALOGENATED SULFONE, QUINAZOLINE AND TRIAZINE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1986-04-22 US disclosed