Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 15/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769205 | 0.79 | SLC6A4 (0.56) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL7474036 | 0.73 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL9769381 | 0.72 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL20054216 | 0.66 | GABBR2 (0.37) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL9769327 | 0.64 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL12646286 | 0.64 | SLC6A4 (0.47) | SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL681660 | 0.63 | SLC6A4 (0.54) | SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL27572922 | 0.63 | GABBR2 (0.45) | — | |
| SCHEMBL9769323 | 0.63 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL17428477 | 0.63 | TSHR (0.52) | SLC6A4SLC6A2SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030647-A | Anti-inflammatory thienylbenzylamine compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1991-07-09 | — | — | US | disclosed |