SCHEMBL9769412

SCHEMBL9769412

Oc1cccc(-c2cc[c]cc2Cl)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 13/20 0.44
HSD17B2 P37059 11/20 0.44
CYP3A4 P08684 3/20 0.44
CYP2C9 P11712 2/20 0.44
TSHR P16473 1/20 0.39
ESR1 P03372 3/20 0.39
ESR2 Q92731 3/20 0.39
PRKAB2 O43741 1/20 0.38
PRKAG1 P54619 1/20 0.38
PRKAA2 P54646 1/20 0.38
PRKAA1 Q13131 1/20 0.38
PRKAG3 Q9UGI9 1/20 0.38
PRKAG2 Q9UGJ0 1/20 0.38
PRKAB1 Q9Y478 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2B6 P20813 1/20 0.38
CYP2C19 P33261 1/20 0.38
CA12 O43570 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16719582 0.82 HSD17B1 (0.47) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL9648712 0.82 TDO2 (0.40) TSHRESR2
SCHEMBL27588585 0.79 HSD17B1 (0.44) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL2013350 0.79 TAAR1 (0.38) HSD17B1HSD17B2ESR2ALDH1A1
SCHEMBL2093448 0.77 CYP2A6 (0.54) CYP2C9TSHRESR2CYP1A2CYP2C19
SCHEMBL16720244 0.77 HSD17B1 (0.41) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL10413691 0.77 AHR (0.41) ESR2
SCHEMBL4284890 0.76 HSD17B1 (0.44) HSD17B1HSD17B2CYP3A4CYP2C9TSHR
SCHEMBL27555403 0.76 CYP2A6 (0.52) CYP2C9TSHRESR2CYP1A2CYP2C19
SCHEMBL1030907 0.76 CYP2A6 (0.58) HSD17B1HSD17B2CYP3A4CYP2C9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5049474-A Color light-sensitive material FUJI PHOTO FILM CO., LTD (JP) 1991-09-17 US disclosed