SCHEMBL9769433

SCHEMBL9769433

CC(=O)Nc1ccc(Cl)c(NC2=NN(c3c(Cl)cc(Cl)cc3Cl)C(=O)C2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
L3MBTL1 Q9Y468 3/20 0.50
MAPT P10636 2/20 0.50
POLB P06746 2/20 0.50
RECQL P46063 2/20 0.50
THRB P10828 1/20 0.50
HTT P42858 1/20 0.50
ATAD2 Q6PL18 1/20 0.41
CECR2 Q9BXF3 1/20 0.41
GAA P10253 2/20 0.39
ALOX12 P18054 1/20 0.39
IGF1R P08069 4/20 0.38
PYGL P06737 1/20 0.38
ACLY P53396 1/20 0.38
GRK5 P34947 1/20 0.37
CDK8 P49336 1/20 0.37
ALDH1A1 P00352 2/20 0.37
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11069491 0.90 POLB (0.47) MEN1KMT2AL3MBTL1MAPTPOLB
SCHEMBL9195282 0.84 SMN1; SMN2 (0.45) MEN1KMT2AL3MBTL1MAPTPOLB
SCHEMBL9344030 0.84 MEN1 (0.57) MEN1KMT2AL3MBTL1MAPTPOLB
SCHEMBL14400382 0.83 MEN1 (0.43) MEN1KMT2AL3MBTL1MAPTPOLB
SCHEMBL12126416 0.83 KMT2A (0.45) MEN1KMT2AL3MBTL1MAPTPOLB
SCHEMBL14045221 0.83 MEN1 (0.41) MEN1KMT2AL3MBTL1MAPTPOLB
SCHEMBL10613765 0.81 KMT2A (0.42) MEN1KMT2AL3MBTL1MAPTPOLB
SCHEMBL14429748 0.80 LMNA (0.43) MEN1KMT2AL3MBTL1MAPTPOLB
SCHEMBL9769455 0.78 KMT2A (0.45) MEN1KMT2AL3MBTL1MAPTPOLB
SCHEMBL11629203 0.77 MAPT (0.39) MEN1KMT2AL3MBTL1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070128560-A1 Photographic element with speed-enhancing compound EASTMAN KODAK COMPANY 2007-06-07 US disclosed
US-5064742-A Dry image-forming process using thermal solvents FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US disclosed
US-4455363-A Heat-developable color photographic material with polymeric color coupler FUJI PHOTO FILM CO., LTD. (JP) 1984-06-19 US disclosed
US-4436808-A MAGENTA COLOR IMAGE FORMING POLYMER COUPLE FROM A PYRAZOLINE-CONTAINING MONOMER FUJI PHOTO FILM CO., LTD. (JP) 1984-03-13 US disclosed