Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769491 | 0.97 | TBXAS1 (0.35) | ALOX5TBXAS1CYP4F2CYP4A11PPARG | |
| SCHEMBL9769494 | 0.94 | ALOX5 (0.35) | ALOX5TBXAS1CYP4F2CYP4A11PPARG | |
| Hydrochloric Acid SCHEMBL9769504 | 0.94 | ALOX5 (0.34) | ALOX5TBXAS1CYP4F2CYP4A11PPARG | |
| SCHEMBL9029933 | 0.89 | ALOX5 (0.36) | ALOX5TBXAS1PPARG | |
| SCHEMBL9031497 | 0.89 | CNR1 (0.34) | ALOX5MTNR1AMTNR1B | |
| SCHEMBL9030229 | 0.88 | TBXAS1 (0.34) | TBXAS1PPARG | |
| SCHEMBL9031371 | 0.87 | ALOX5 (0.38) | ALOX5CYP4F2CYP4A11PPARG | |
| SCHEMBL9769515 | 0.87 | TBXAS1 (0.35) | ALOX5TBXAS1CYP4F2CYP4A11 | |
| SCHEMBL9029704 | 0.87 | PPARA (0.34) | ALOX5TBXAS1PPARG | |
| SCHEMBL9676919 | 0.87 | PPARG (0.34) | ALOX5TBXAS1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375746-A1 | HYPOLIPIDAEMIC IMIDAZOL-2-YL-DERIVATIVES OF BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-07-04 | — | — | EP | claimed |
| WO-1989008646-A1 | HYPOLIPIDAEMIC IMIDAZOL-2-YL-DERIVATIVES OF BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-09-21 | — | — | WO | claimed |
| US-4985440-A | Hypolipidaemic imidazol-2-yl-derivatives of bicyclic compounds | FARMITALIA CARLO ERBA, S.R.L. (IT) | 1991-01-15 | — | — | US | disclosed |
| EP-0375746-A1 | HYPOLIPIDAEMIC IMIDAZOL-2-YL-DERIVATIVES OF BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1990-07-04 | — | — | EP | disclosed |
| WO-1989008646-A1 | HYPOLIPIDAEMIC IMIDAZOL-2-YL-DERIVATIVES OF BICYCLIC COMPOUNDS AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.R.L. (IT) | 1989-09-21 | — | — | WO | disclosed |