Mitozolomide

Mitozolomide

SCHEMBL97695

NC(=O)c1ncn2c(=O)n(CCCl)nnc12

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.64
PABPC1 P11940 1/20 0.64
KMT2A Q03164 1/20 0.64
CA12 O43570 3/20 0.39
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA9 Q16790 3/20 0.39
MAPT P10636 1/20 0.31
ADORA2B P29275 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3337129 0.93 MEN1 (0.63) MEN1PABPC1KMT2ACA12CA1
SCHEMBL13027731 0.92 MEN1 (0.71) MEN1PABPC1KMT2ACA12CA1
SCHEMBL13027994 0.89 MEN1 (0.63) MEN1PABPC1KMT2ACA12CA1
SCHEMBL10643552 0.88 MEN1 (0.48) MEN1PABPC1KMT2ACA12CA1
SCHEMBL2891553 0.88 MEN1 (0.66) MEN1PABPC1KMT2ACA12CA1
SCHEMBL10644355 0.88 MEN1 (0.51) MEN1PABPC1KMT2ACA12CA1
SCHEMBL2892060 0.86 MEN1 (0.64) MEN1PABPC1KMT2ACA12CA1
SCHEMBL3336560 0.86 MEN1 (0.68) MEN1PABPC1KMT2ACA12CA1
SCHEMBL13028036 0.86 MEN1 (0.64) MEN1PABPC1KMT2ACA12CA1
SCHEMBL13028034 0.86 MEN1 (0.64) MEN1PABPC1KMT2ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4864 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4663205-A1 POLYMER-DRUG CONJUGATE, INTERMEDIATE THEREOF, AND USE THEREOF Shanghai Best-Link Bioscience, LLC (CN) 2025-12-17 EP claimed
EP-4646432-A1 ANTI-IL-18BP ANTIBODIES Lassen Therapeutics, Inc. (US) 2025-11-12 EP claimed
EP-4646433-A1 ANTI-IL-18BP ANTIBODIES Lassen Therapeutics, Inc. (US) 2025-11-12 EP claimed
US-20250255977-A1 EPSILON-POLY-L-LYSINE-BASED DRUG CONJUGATE, INTERMEDIATE THEREOF, AND APPLICATION THEREOF SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) 2025-08-14 US claimed
EP-4590341-A1 POLYMERS WITH DUAL THERAPEUTIC AGENTS Sony Group Corporation (JP) 2025-07-30 EP claimed
US-20250215505-A1 MGMT EPIGENETIC DEEP-SEQUENCING ASSAY MDXHEALTH SA (BE) 2025-07-03 US claimed
CN-120152742-A Polymer with dual therapeutic agents 索尼集团公司 2025-06-13 CN claimed
US-20250188170-A1 COMPOSITIONS AND METHODS COMPRISING ANTI-NRP2b ANTIBODIES ATYR PHARMA, INC. 2025-06-12 US claimed
US-20250032413-A1 ULTRASONICALLY-ENHANCED CONTINUOUS AND LARGE-SCALE PRODUCTION METHOD FOR NANO-FORMULATIONS SHANGHAI BEST-LINK BIOSCIENCE, LLC (CN) 2025-01-30 US claimed
US-20250009786-A1 AUTOMATED SYNTHESIS OF POLYMERIC DUAL DRUGS Sony Group Corporation (JP) 2025-01-09 US claimed
CN-1679952-A Anticarcinogenic medicine composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1679946-A Anticarcinogen composition LANJIN BIOLOG ENGINEERING CO L (CN) 2005-10-12 CN claimed
CN-1660436-A Anticancer combination of medication LANJIN BIOLOG ENGINEERING CO L (CN) 2005-08-31 CN claimed
WO-2005068465-A1 2-AMINO-O4-SUBSTITUTED PTERIDINES AND THEIR USE AS INACTIVATORS OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2005-07-28 WO claimed
CN-1628850-A Anti solid tumor medicine composition KONG QINGZHONG (CN) 2005-06-22 CN claimed
CN-1628849-A Anticancer medicine composition KONG QINGZHONG (CN) 2005-06-22 CN claimed
CN-1628851-A Anti-cancer medicine composition KONG QINGZHONG (CN) 2005-06-22 CN claimed
CN-1616098-A Anti-cancer medicine composition KONG QINGZHONG (CN) 2005-05-18 CN claimed
WO-2005025620-A2 COMBINATION THERAPY WITH INHIBITORS OF INDUCIBLE NITRIC OXIDE SYNTHASE AND ALKYLATING AGENTS PHARMACIA CORPORATION (US) 2005-03-24 WO claimed
US-5260291-A Tetrazine derivatives CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 1993-11-09 US claimed