Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10644355 | 0.89 | MEN1 (0.51) | MEN1PABPC1KMT2ACA12CA1 | |
| Mitozolomide SCHEMBL97695 | 0.88 | MEN1 (0.64) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3336299 | 0.84 | MEN1 (0.47) | MEN1PABPC1KMT2ACA12CA1 | |
| Water SCHEMBL10648619 | 0.83 | MEN1 (0.46) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL31452072 | 0.81 | MEN1 (0.41) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL10648478 | 0.81 | MEN1 (0.44) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3337129 | 0.81 | MEN1 (0.63) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL891470 | 0.80 | MEN1 (0.73) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL4246136 | 0.80 | CA12 (0.42) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL10648222 | 0.78 | MAPT (0.41) | MEN1PABPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283280-A1 | IMIDAZOTETRAZINONE-BASED COMBI-MOLECULES | JEAN-CLAUDE BERTRAND (CA) | 2012-11-08 | — | — | US | disclosed |
| US-20120283280-A1 | IMIDAZOTETRAZINONE-BASED COMBI-MOLECULES | JEAN-CLAUDE BERTRAND (CA) | 2012-11-08 | — | — | US | disclosed |
| EP-0252682-A2 | Tetrazines | MAY & BAKER LIMITED (GB) | 1988-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120283280-A1 | IMIDAZOTETRAZINONE-BASED COMBI-MOLECULES | EGFR, ERBB2, ERBB4 | MEN1 3490/4885PABPC1 3839/4885KMT2A 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.