SCHEMBL6208231

SCHEMBL6208231

Cc1cc(C2(c3ccc(O)c(C)c3)c3ccccc3-c3ccccc32)ccc1O.Oc1ccc(C2(c3ccc(O)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.88
ESR2 Q92731 5/20 0.88
LMNA P02545 5/20 0.54
MAPT P10636 5/20 0.54
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
POLB P06746 3/20 0.54
TDP1 Q9NUW8 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
XBP1 P17861 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KDM4E B2RXH2 1/20 0.46
OPRK1 P41145 1/20 0.46
GPR55 Q9Y2T6 5/20 0.42
CNR1 P21554 3/20 0.42
HTT P42858 1/20 0.42
GPR35 Q9HC97 1/20 0.42
CHRM2 P08172 1/20 0.40
ADORA3 P0DMS8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17399575 1.00 ESR1 (0.88) ESR1ESR2LMNAMAPTMEN1
SCHEMBL15691554 0.95 ESR1 (0.97) ESR1ESR2LMNAMAPTMEN1
SCHEMBL29450641 0.94 ESR1 (1.00) ESR1ESR2LMNAMAPTMEN1
SCHEMBL70957 0.94 ESR1 (1.00) ESR1ESR2LMNAMAPTMEN1
SCHEMBL29358768 0.94 ESR1 (1.00) ESR1ESR2LMNAMAPTMEN1
SCHEMBL12084149 0.90 ESR1 (0.93) ESR1ESR2LMNAMAPTMEN1
SCHEMBL12387987 0.89 ESR1 (0.90) ESR1ESR2LMNAMAPTMEN1
SCHEMBL18386002 0.89 ESR1 (0.90) ESR1ESR2LMNAMAPTMEN1
SCHEMBL10697013 0.88 ESR1 (0.88) ESR1ESR2LMNAMAPTMEN1
SCHEMBL465366 0.87 ESR1 (0.70) ESR1ESR2LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138714-B1 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL CO (JP) 2005-02-23 EP claimed