Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769553 | 0.94 | ALDH1A1 (0.58) | NPSR1ALDH1A1ALOX15POLBATM | |
| SCHEMBL28147856 | 0.87 | KDM4E (0.56) | NPSR1ALDH1A1ALOX15POLBKMT2A | |
| SCHEMBL28659962 | 0.87 | ALDH1A1 (0.49) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL5868364 | 0.86 | ALDH1A1 (0.54) | NPSR1ALDH1A1ALOX15KMT2ANPC1 | |
| SCHEMBL11674348 | 0.86 | POLB (0.66) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL11673653 | 0.86 | KMT2A (0.53) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL28672305 | 0.86 | HPGD (0.51) | NPSR1ALDH1A1ALOX15POLBKMT2A | |
| SCHEMBL10949416 | 0.84 | NPSR1 (0.50) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL407836 | 0.84 | L3MBTL1 (0.50) | NPSR1ALDH1A1POLBKMT2ANPC1 | |
| SCHEMBL9001692 | 0.83 | NPSR1 (0.61) | NPSR1ALDH1A1ALOX15POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041667-A | Process for producing chlorophenylhydrazine compounds | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0197478-B1 | DIPHOSPHONIC-ACID DERIVATIVES, PROCESS FOR PREPARING THEM AND MEDICINES CONTAINING THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1990-09-19 | — | — | EP | disclosed |
| EP-0208477-A1 | Process for producing chlorophenylhydrazine compounds | KONICA CORPORATION (JP) | 1987-01-14 | — | — | EP | disclosed |
| EP-0197478-A1 | Diphosphonic-acid derivatives, process for preparing them and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1986-10-15 | — | — | EP | disclosed |