SCHEMBL9769557

SCHEMBL9769557

O=C(Cl)c1ccc(Oc2ccc(S(=O)(=O)c3ccc(Oc4ccc(C(=O)Cl)cc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
APEX1 P27695 1/20 0.55
CTDSP1 Q9GZU7 1/20 0.55
HTT P42858 4/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
PKM P14618 3/20 0.48
MAPT P10636 2/20 0.48
ALDH1A1 P00352 5/20 0.46
KMT2A Q03164 2/20 0.45
PARP15 Q460N3 1/20 0.45
PARP14 Q460N5 1/20 0.45
PARP10 Q53GL7 1/20 0.45
PARP16 Q8N5Y8 1/20 0.45
PARP11 Q9NR21 1/20 0.45
PARP4 Q9UKK3 1/20 0.45
HPGD P15428 1/20 0.45
RAB9A P51151 1/20 0.45
ELANE P08246 1/20 0.44
TDP1 Q9NUW8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL724893 0.88 ALDH1A1 (0.50) POLBL3MBTL1PKMMAPTALDH1A1
SCHEMBL9242846 0.87 ALDH1A1 (0.44) POLBL3MBTL1APEX1CTDSP1HTT
SCHEMBL7994787 0.87 ALDH1A1 (0.44) POLBL3MBTL1APEX1CTDSP1HTT
SCHEMBL272345 0.85 PARP10 (0.58) HTTSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL9786679 0.85 PARP10 (0.58) HTTSMN1; SMN2MAPTALDH1A1KMT2A
SCHEMBL10496995 0.83 HTT (0.55) POLBL3MBTL1APEX1CTDSP1HTT
SCHEMBL1634512 0.82 POLB (0.76) POLBL3MBTL1APEX1CTDSP1HTT
SCHEMBL9855503 0.82 POLB (0.76) POLBL3MBTL1APEX1CTDSP1HTT
SCHEMBL11050987 0.82 POLB (0.76) POLBL3MBTL1APEX1CTDSP1HTT
SCHEMBL17370930 0.81 MAPT (0.73) POLBL3MBTL1APEX1CTDSP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9273181-B2 Polyester-based polymer having superior transparency and high heat resistance and preparation of the same IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2016-03-01 US disclosed
US-9273181-B2 Polyester-based polymer having superior transparency and high heat resistance and preparation of the same IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY) (KR) 2016-03-01 US disclosed
US-20150376329-A1 NOVEL POLYESTER-BASED POLYMER HAVING SUPERIOR TRANSPARENCY AND HIGH HEAT RESISTANCE AND PREPARATION OF THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2015-12-31 US disclosed
US-20150376329-A1 NOVEL POLYESTER-BASED POLYMER HAVING SUPERIOR TRANSPARENCY AND HIGH HEAT RESISTANCE AND PREPARATION OF THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY (KR) 2015-12-31 US disclosed
US-4992526-A Preparation of polyarylate polymers of hydroxyaryl-substituted 1,6-diaza [4.] spirodilactams SHELL OIL COMPANY (US) 1991-02-12 US disclosed
US-4977235-A From aromatic dicarboxylic acids and hydroxyaryl-substituted 1,6-diaza(4.4)spirodilactams; molding materials; high glass transition temperatures SHELL OIL COMPANY (US) 1990-12-11 US disclosed
US-4910285-A Polyarylate polymers SHELL OIL COMPANY (US) 1990-03-20 US disclosed