SCHEMBL9769565

SCHEMBL9769565

C=C(C)C(=O)OCCCNS(=O)(=O)O

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.51
THRB P10828 1/20 0.44
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 4/20 0.38
LMNA P02545 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CA2 P00918 3/20 0.32
CA12 O43570 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA1 P00915 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9418366 0.89 THRB (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11964812 0.86 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15473378 0.82 TSHR (0.47) TSHRTHRBPOLBAPEX1HTT
SCHEMBL775568 0.81 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL1798323 0.78 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL107954 0.78 TSHR (0.58) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9313454 0.77 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
Sulfuric Acid SCHEMBL1683726 0.77 THRB (0.63) TSHRTHRBPOLBAPEX1HTT
SCHEMBL182045 0.77 TSHR (0.72) TSHRTHRBPOLBAPEX1HTT
SCHEMBL25426 0.77 TSHR (0.79) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5073471-A Comprising dispersed resin grains of an acrylic polymer of an unsaturated ester, an acrylic stabilizer and an oligomer; antisoilants; antisticking agents FUJI PHOTO FILM CO., LTD. (JP) 1991-12-17 US disclosed
US-5041352-A Dispersion stability, ink receptivity FUJI PHOTO FILM CO., LTD. (JP) 1991-08-20 US disclosed
US-4977055-A RESIN DISPESEDIN NONAQUEOUS SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1990-12-11 US disclosed