Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769756 | 0.84 | TSHR (0.48) | KMT2AMEN1HCAR3CASP6LMNA | |
| SCHEMBL9769718 | 0.82 | KMT2A (0.43) | KMT2AMEN1HCAR3CASP6LMNA | |
| SCHEMBL10467005 | 0.68 | KMT2A (0.44) | KMT2AMEN1HCAR3CASP6KDM4E | |
| SCHEMBL4720311 | 0.67 | MAPT (0.63) | KMT2AMEN1CASP6ALOX5KDM4E | |
| SCHEMBL30657600 | 0.67 | CASP6 (0.60) | KMT2AMEN1HCAR3CASP6KDM4E | |
| SCHEMBL29126952 | 0.67 | CASP6 (0.60) | KMT2AMEN1HCAR3CASP6KDM4E | |
| SCHEMBL2292095 | 0.67 | CASP6 (0.64) | HCAR3CASP6POLBLMNATSHR | |
| SCHEMBL99918 | 0.67 | CASP6 (0.64) | HCAR3CASP6POLBLMNATSHR | |
| SCHEMBL9585913 | 0.66 | KMT2A (0.47) | KMT2AMEN1KDM4EPOLBLMNA | |
| SCHEMBL12292886 | 0.64 | GAA (0.62) | KMT2AMEN1HCAR3CASP6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071994-A | Intermediates for positive working photographic compounds, analgesics; anti-inflammatory agents | FUJI PHOTO FILM CO., LTD. (JP) | 1991-12-10 | — | — | US | disclosed |
| US-4950764-A | HERBICIDES, BACTERICIDES, ANALGESICS, ANTIINFLAMMATORY AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 1990-08-21 | — | — | US | disclosed |