Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | HCAR3 | P49019 | 8/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9557826 | 0.92 | CASP6 (0.66) | CASP6TSHRLMNATDP1HCAR3 | |
| SCHEMBL23499234 | 0.90 | CASP6 (0.64) | CASP6TSHRLMNATDP1HCAR3 | |
| SCHEMBL30011381 | 0.90 | CASP6 (0.64) | CASP6TSHRLMNATDP1HCAR3 | |
| SCHEMBL17197945 | 0.90 | CASP6 (0.68) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL11195885 | 0.88 | CASP6 (0.75) | CASP6TSHRLMNAHCAR3APEX1 | |
| SCHEMBL9171787 | 0.87 | ALDH1A1 (0.54) | CASP6TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL8441836 | 0.87 | MAPT (0.59) | CASP6TSHRALDH1A1TDP1POLB | |
| SCHEMBL11696700 | 0.87 | ALDH1A1 (0.54) | CASP6TSHRLMNAALDH1A1TDP1 | |
| SCHEMBL27940022 | 0.87 | VCAM1 (0.66) | CASP6LMNAALDH1A1TDP1HCAR3 | |
| SCHEMBL31548567 | 0.87 | CASP6 (0.64) | CASP6TSHRLMNAALDH1A1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118496135-B | Thiourea compound or pharmaceutically acceptable salt thereof and application thereof as immunosuppressant | 中国海洋大学 | 2024-11-15 | — | — | CN | disclosed |
| CN-118496135-A | Thiourea compound or pharmaceutically acceptable salt thereof and application thereof as immunosuppressant | 中国海洋大学 | 2024-08-16 | — | — | CN | disclosed |
| CN-118401507-A | Inhibitors targeting ubiquitin-specific protease 7 (USP 7) | 丹娜法伯癌症研究院 | 2024-07-26 | — | — | CN | disclosed |
| CN-109467509-B | Preparation method of substituted nitrobenzene compounds | 联化科技股份有限公司 | 2021-09-24 | — | — | CN | disclosed |
| US-9072734-B2 | Quaternary ammonium salt compounds | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| CN-102459231-B | Quaternary ammonium salt compound | TEIJIN PHARMA LTD | 2015-04-22 | — | — | CN | disclosed |
| CN-102459231-A | Quaternary ammonium salt compound | TEIJIN PHARMA LTD | 2012-05-16 | — | — | CN | disclosed |
| CN-101923241-B | Display element | SHARP KK | 2012-05-09 | — | — | CN | disclosed |
| CN-1960969-B | Histamine H3 receptor agents, methods of preparation and therapeutic uses thereof | LILLY CO ELI | 2012-03-28 | — | — | CN | disclosed |
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| CN-101583352-A | Preparation and use of biphenyl amino acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORP (US) | 2009-11-18 | — | — | CN | disclosed |
| CN-100476522-C | Display element and display apparatus | SHARP KK (JP) | 2009-04-08 | — | — | CN | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
| CN-101087769-A | Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORP (US) | 2007-12-12 | — | — | CN | disclosed |
| CN-101018774-A | Modulators of alpha7 nicotinic acetylcholine receptors and therapeutic uses thereof | SIENA BIOTECH SPA (IT) | 2007-08-15 | — | — | CN | disclosed |
| CN-1960969-A | Histamine H3 receptor agents, methods of preparation and therapeutic uses thereof | LILLY CO ELI (US) | 2007-05-09 | — | — | CN | disclosed |
| EP-1697337-A2 | ORNITHINE DERIVATIVES AS PROSTAGLANDIN-E2-AGONISTS OR ANTAGONISTS | Astellas Pharma Inc. (JP) | 2006-09-06 | — | — | EP | disclosed |
| CN-1645192-A | Display element and display apparatus | SHARP KK (JP) | 2005-07-27 | — | — | CN | disclosed |
| CN-1641425-A | Display element, display device, and method for manufacturing display element | SHARP KK (JP) | 2005-07-20 | — | — | CN | disclosed |
| WO-2005061475-A2 | ORNITHINE DERIVATIVES AS PROSTAGLANDIN E2 AGONISTS OR ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2005-07-07 | — | — | WO | disclosed |