SCHEMBL976979

SCHEMBL976979

Fc1cc(F)c(-c2c(Cl)nc3ncnn3c2NCC(F)(F)F)c(F)c1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MBOAT4 Q96T53 5/20 0.35
ALDH1A1 P00352 6/20 0.35
KMT2A Q03164 2/20 0.35
TSHR P16473 2/20 0.35
POLB P06746 1/20 0.35
KDM4E B2RXH2 3/20 0.34
MAPK1 P28482 2/20 0.34
HPGD P15428 2/20 0.34
GAA P10253 3/20 0.33
MEN1 O00255 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31020443 0.91 MBOAT4 (0.34) MBOAT4ALDH1A1KMT2ATSHRPOLB
SCHEMBL4817631 0.88 MBOAT4 (0.38) MBOAT4ALDH1A1KMT2ATSHRPOLB
SCHEMBL6186573 0.88 MBOAT4 (0.38) MBOAT4ALDH1A1KMT2ATSHRPOLB
SCHEMBL6995496 0.87 MAPK1 (0.39) MBOAT4ALDH1A1KMT2ATSHRPOLB
SCHEMBL975025 0.86 MBOAT4 (0.44) MBOAT4ALDH1A1KMT2ATSHRPOLB
SCHEMBL7821240 0.86 ENPP1 (0.42) ALDH1A1KMT2ATSHRPOLBMAPK1
SCHEMBL7960580 0.86 ALDH1A1 (0.38) MBOAT4ALDH1A1KMT2ATSHRPOLB
SCHEMBL4821587 0.84 ALDH1A1 (0.33) MBOAT4ALDH1A1KMT2ATSHRPOLB
SCHEMBL3220251 0.84 MBOAT4 (0.34) MBOAT4ALDH1A1KMT2ATSHRPOLB
SCHEMBL4819483 0.83 MBOAT4 (0.36) MBOAT4ALDH1A1KMT2ATSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090149455-A1 Use of Triazolopyrimidines for Controlling Plant Diseases on Legumes BAYER CROPSCIENCE AG (DE) 2009-06-11 US claimed
EP-1893021-A2 USE OF TRIAZOLOPYRIMIDINES FOR CONTROLLING PLANT DISEASES ON LEGUMES Bayer CropScience AG (DE) 2008-03-05 EP claimed
WO-2006131223-A2 USE OF TRIAZOLOPYRIMIDINES FOR CONTROLLING RUST DISEASES ON LEGUMES BAYER CROPSCIENCE AG (DE) 2006-12-14 WO claimed
EP-0975635-B1 FUNGICIDAL TRIFLUOROMETHYLALKYLAMINO-TRIAZOLOPYRIMIDINES BASF AG (DE) 2003-05-07 EP claimed
EP-0975634-B1 FUNGICIDAL TRIFLUOROPHENYL-TRIAZOLOPYRIMIDINES BASF AG (DE) 2001-07-04 EP claimed
EP-4653442-A1 POLYCYCLIC COMPOUND FOR TREATING NEUROLOGICAL DISEASES AND TUMORS SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) 2025-11-26 EP disclosed
WO-2024153202-A1 POLYCYCLIC COMPOUND FOR TREATING NEUROLOGICAL DISEASES AND TUMORS 中国科学院上海有机化学研究所 2024-07-25 WO disclosed
EP-2903436-B1 HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES UNIV PENNSYLVANIA (US) 2019-07-17 EP disclosed
EP-2903436-B1 HETEROCYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEURODEGENERATIVE TAUOPATHIES UNIV PENNSYLVANIA (US) 2019-07-17 EP disclosed
US-10131816-B2 Amic acids as surface treatments HUDSON ALICE (US) 2018-11-20 US disclosed
US-20180194965-A1 Amic acids as surface treatments HUDSON ALICE (US) 2018-07-12 US disclosed
US-9926466-B2 Amic acids as surface treatments HUDSON ALICE (US) 2018-03-27 US disclosed
EP-0975635-B1 FUNGICIDAL TRIFLUOROMETHYLALKYLAMINO-TRIAZOLOPYRIMIDINES BASF AG (DE) 2003-05-07 EP disclosed
US-6297251-B1 Fungicidal trifluorophenyl-triazolopyrimidines AMERICAN CYANAMID CO. 2001-10-02 US disclosed
EP-0975634-B1 FUNGICIDAL TRIFLUOROPHENYL-TRIAZOLOPYRIMIDINES BASF AG (DE) 2001-07-04 EP disclosed
US-6117876-A Fungicidal trifluorophenyl-triazolopyrimidines AMERICAN CYANAMID COMPANY (US) 2000-09-12 US disclosed
EP-0975635-A1 FUNGICIDAL TRIFLUOROMETHYLALKYLAMINO-TRIAZOLOPYRIMIDINES AMERICAN CYANAMID COMPANY (US) 2000-02-02 EP disclosed
EP-0975634-A1 FUNGICIDAL TRIFLUOROPHENYL-TRIAZOLOPYRIMIDINES AMERICAN CYANAMID COMPANY (US) 2000-02-02 EP disclosed
WO-1998046607-A1 FUNGICIDAL TRIFLUOROPHENYL-TRIAZOLOPYRIMIDINES AMERICAN CYANAMID COMPANY (US) 1998-10-22 WO disclosed
WO-1998046608-A1 FUNGICIDAL TRIFLUOROMETHYLALKYLAMINO-TRIAZOLOPYRIMIDINES AMERICAN CYANAMID COMPANY (US) 1998-10-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090149455-A1 Use of Triazolopyrimidines for Controlling Plant Diseases on Legumes TYMP, CCNT2, PNPO MBOAT4 4743/4885ALDH1A1 3022/4885KMT2A 1970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.