SCHEMBL9769810

SCHEMBL9769810

O=C(O)c1cc(-c2cccc(C3CCCCC3)c2)ccc1O

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACMSD Q8TDX5 12/20 0.71
MCL1 Q07820 5/20 0.58
DHFR P00374 1/20 0.58
HNF4A P41235 1/20 0.58
KMO O15229 1/20 0.56
HDAC4 P56524 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
LCK P06239 1/20 0.48
DHODH Q02127 1/20 0.46
SERPINE1 P05121 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2533359 0.84 ACMSD (1.00) ACMSDMCL1DHFRHNF4AKMO
SCHEMBL27965931 0.84 ACMSD (1.00) ACMSDMCL1DHFRHNF4AKMO
SCHEMBL11773406 0.80 ACMSD (0.66) ACMSDHNF4AKMOHDAC4HDAC2
SCHEMBL9849967 0.78 ACMSD (0.67) ACMSDKMOHDAC4HDAC2HDAC8
SCHEMBL8376912 0.78 ACMSD (0.63) ACMSDKMOHDAC4HDAC2HDAC8
SCHEMBL22816805 0.77 MEN1 (0.53) ACMSDKMOHDAC4HDAC2HDAC8
SCHEMBL10888149 0.77 ACMSD (0.65) ACMSDKMOHDAC4HDAC2HDAC8
SCHEMBL9769794 0.77 KMO (0.55) ACMSDKMOHDAC4HDAC2HDAC8
SCHEMBL778007 0.77 KMO (0.56) ACMSDKMOHDAC4HDAC2HDAC8
SCHEMBL27881571 0.75 ACMSD (0.86) ACMSDMCL1DHFRHNF4ALCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed