SCHEMBL9769820

SCHEMBL9769820

O=C(Oc1cccc(Cc2ccccc2)c1)c1ccccc1Oc1cccc(Cc2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 2/20 0.50
TSHR P16473 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.48
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
GAA P10253 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CTNNB1 P35222 1/20 0.45
MAPT P10636 2/20 0.45
KDM4E B2RXH2 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
MEN1 O00255 2/20 0.43
MAPK1 P28482 1/20 0.43
HPGD P15428 1/20 0.43
ALOX15 P16050 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.42
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769842 0.81 PPARA (0.55) MAPTLMNA
SCHEMBL767125 0.78 CTNNB1 (0.65) KMT2AHSD17B10ALDH1A1TSHRSMN1; SMN2
SCHEMBL9850074 0.78 CYP2C19 (0.69) KMT2AHSD17B10ALDH1A1CYP1A2CYP3A4
SCHEMBL9719824 0.77 KDM4E (0.51) KMT2AHSD17B10ALDH1A1TSHRSMN1; SMN2
SCHEMBL10517016 0.77 MTNR1A (0.43) ALOX15PTGDR2BCHEACHE
SCHEMBL8373101 0.76 PTGS1 (0.49) KMT2AHSD17B10ALDH1A1TSHRSMN1; SMN2
SCHEMBL5697818 0.76 MAPT (0.48) KMT2AHSD17B10ALDH1A1TSHRSMN1; SMN2
SCHEMBL28055585 0.76 ACHE (0.47) KMT2AALDH1A1MAPTBCHEACHE
SCHEMBL9150822 0.75 MTNR1A (0.41) KMT2AALDH1A1GAAKDM4EMEN1
SCHEMBL9150816 0.75 MTNR1A (0.41) KMT2AALDH1A1GAAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed
US-3983292-A Pressure sensitive recording papers SANKO CHEMICAL COMPANY LTD. (JA) 1976-09-28 US disclosed