SCHEMBL9769909

SCHEMBL9769909

CCc1cccc(CCc2cccc(C(=O)O)c2O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.56
HTT P42858 1/20 0.48
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
PTPN1 P18031 3/20 0.43
BCL2 P10415 1/20 0.43
PTPN2 P17706 1/20 0.43
PTPN6 P29350 1/20 0.43
CLCN2 P51788 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
EGFR P00533 1/20 0.41
LCK P06239 1/20 0.41
SCN1A P35498 2/20 0.41
SCN2A Q99250 2/20 0.41
SCN3A Q9NY46 2/20 0.41
SOX18 P35713 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11710019 0.88 HTT (0.57) HTTKDM4EALDH1A1BCL2CLCN2
SCHEMBL301121 0.84 HMGB1 (0.67) HMGB1HTTKDM4EALDH1A1HPGD
SCHEMBL39623 0.81 HMGB1 (0.65) HMGB1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL29695710 0.81 HMGB1 (0.65) HMGB1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL10581740 0.80 HMGB1 (0.50) HMGB1HTTKDM4EALDH1A1HPGD
SCHEMBL18790581 0.80 IAPP (0.50) GABRA1GABRB2SOX18EP300KAT5
SCHEMBL9859 0.79 HMGB1 (0.69) HMGB1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL27360496 0.79 HMGB1 (0.62) HMGB1KDM4EALDH1A1HPGDHSD17B10
Bicarbonate SCHEMBL237485 0.79 HMGB1 (0.62) HMGB1KDM4EALDH1A1HPGDHSD17B10
Hydrochloric Acid SCHEMBL11527302 0.79 HMGB1 (0.62) HMGB1KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4999333-A For facsimile and thermal printing FUJI PHOTO FILM CO., LTD. (JP) 1991-03-12 US disclosed