Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | IAPP | P10997 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 2/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL236594 | 0.98 | HMGB1 (0.67) | HMGB1KDM4EALDH1A1HPGDHSD17B10 | |
| Bicarbonate SCHEMBL22573123 | 0.98 | HMGB1 (0.67) | HMGB1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL39812 | 0.89 | HMGB1 (0.65) | HMGB1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4636544 | 0.89 | HMGB1 (0.55) | HMGB1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27347887 | 0.88 | HMGB1 (0.63) | HMGB1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL300854 | 0.88 | HMGB1 (0.63) | HMGB1KDM4EHSD17B10MMP2BID | |
| Bicarbonate SCHEMBL22573105 | 0.88 | HMGB1 (0.63) | HMGB1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL4649025 | 0.88 | HMGB1 (0.63) | HMGB1KDM4EALDH1A1HPGDHSD17B10 | |
| Bicarbonate SCHEMBL237561 | 0.88 | HMGB1 (0.63) | HMGB1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7028825 | 0.87 | HMGB1 (0.51) | HMGB1IAPPGABRA1GABRB2PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 19855 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12629393-B2 | Pharmaceutical composition for preventing or treating osteoarthritis | KOLON LIFE SCIENCE, INC. (KR) | 2026-05-19 | — | — | US | claimed |
| CN-122056930-A | Method for establishing animal model of premature ovarian failure rat based on enterovirus group transplantation | 济南微生态生物医学省实验室 | 2026-05-19 | — | — | CN | claimed |
| WO-2026101221-A1 | NOVEL COMPOUND | 아주대학교 산학협력단 | 2026-05-15 | — | — | WO | claimed |
| WO-2026101215-A1 | COMPOSITION FOR INHIBITING HEPATITIS B VIRUS (HBV) PROLIFERATION | 아주대학교 산학협력단 | 2026-05-15 | — | — | WO | claimed |
| WO-2026100969-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING SARCOPENIA | 아주대학교 산학협력단 | 2026-05-15 | — | — | WO | claimed |
| WO-2026101222-A1 | NOVEL COMPOUND | 아주대학교 산학협력단 | 2026-05-15 | — | — | WO | claimed |
| WO-2026101218-A1 | NOVEL COMPOUND AND COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR INHIBITING HEPATITIS B VIRUS (HBV) PROLIFERATION | 아주대학교 산학협력단 | 2026-05-15 | — | — | WO | claimed |
| EP-4327813-B1 | COADMINISTRATION OF MIRODENAFIL WITH CORT-108297 FOR PREVENTING AND TREATING DEMENTIA | ARIBIO CO LTD (KR) | 2026-04-08 | — | — | EP | claimed |
| EP-4161543-B1 | COMPOSITIONS AND METHODS FOR INHIBITING THE PROLIFERATION OF PATHOGENIC ESCHERICHIA COLI | INTRON BIOTECHNOLOGY INC (KR) | 2026-01-28 | — | — | EP | claimed |
| EP-4661841-A1 | DEGARELIX ORGANIC SOLVENT FORMULATIONS | Tolmar International Limited (IE) | 2025-12-17 | — | — | EP | claimed |
| WO-2001032210-A2 | COMPOSITIONS FOR TREATING ATHEROMA AND NEOPLASTIC TISSUE | PHARMACYCLICS, INC. (US) | 2001-05-10 | — | — | WO | claimed |
| WO-2000050036-A1 | STORAGE STABLE AMOXYCILLIN AND CLAVULANATE SUSPENSION COMPOSITION | BIOVAIL INTERNATIONAL LTD. (US) | 2000-08-31 | — | — | WO | claimed |
| EP-0793495-B1 | FREEZE-DRIED ONDANSETRON COMPOSITIONS | GLAXO WELLCOME INC (CA) | 2000-05-31 | — | — | EP | claimed |
| US-6066629-A | DRY POWDER; MIXTURE CONTAINING LACTAMASE INHIBITOR | FUISZ TECHNOLOGIES LTD. (US) | 2000-05-23 | — | — | US | claimed |
| CN-1202881-A | Process for preparing a perfuming composition and a perfumed product, and resulting product | RHODIA CHIMIE SA (FR) | 1998-12-23 | — | — | CN | claimed |
| EP-0451300-B1 | Composition containing a colloidal barium sulphate dispersion | KOWALSKI ROMUALD DR (PL) | 1994-10-26 | — | — | EP | claimed |
| EP-0421825-A1 | Paracetamol solutions | KADEM FARMASEUTIESE PRODUKTIE B.K. (ZA) | 1991-04-10 | — | — | EP | claimed |
| US-4658826-A | Skin preparatory composition for use with electrocardiograph and electroencephalograph monitoring electrodes | D. O. Weaver and Company (US) | 1987-04-21 | — | — | US | claimed |
| US-RE32112-E | Spironolactone-containing composition and use thereof | Shapiro, German (US) | 1986-04-15 | — | — | US | claimed |
| US-4347245-A | Spironolactone-containing composition and use thereof | SHAPIRO GERMAN | 1982-08-31 | — | — | US | claimed |