SCHEMBL9769947

SCHEMBL9769947

CCCCC(CC)Cn1c(=O)c(Cl)c(Cl)n(C)c1=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.42
TP53 P04637 1/20 0.42
CYP3A4 P08684 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
RECQL P46063 1/20 0.33
ALDH1A1 P00352 6/20 0.33
KDM4E B2RXH2 3/20 0.33
HPGD P15428 3/20 0.33
GAA P10253 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
CHRM2 P08172 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
CHRM1 P11229 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12179829 0.77 MAPT (0.38) MAPTTP53CYP3A4L3MBTL1ALDH1A1
SCHEMBL9769944 0.76 MAPT (0.41) MAPTTP53CYP3A4L3MBTL1CYP1A2
SCHEMBL19392294 0.72 ALDH1A1 (0.41) MAPTTP53CYP3A4L3MBTL1ALDH1A1
SCHEMBL12179833 0.69 ALDH1A1 (0.39) MAPTTP53CYP3A4L3MBTL1ALDH1A1
SCHEMBL12179865 0.68 MAPT (0.38) MAPTTP53CYP3A4L3MBTL1ALDH1A1
SCHEMBL12179806 0.68 MAPT (0.38) MAPTTP53CYP3A4L3MBTL1ALDH1A1
SCHEMBL16265459 0.67 ALDH1A1 (0.42) MAPTTP53CYP3A4L3MBTL1ALDH1A1
SCHEMBL5335314 0.67 ALDH1A1 (0.40) MAPTTP53CYP3A4L3MBTL1ALDH1A1
SCHEMBL34464729 0.66 MAPT (0.38) MAPTTP53CYP3A4ALDH1A1KDM4E
SCHEMBL34464728 0.66 MAPT (0.38) MAPTTP53CYP3A4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5066573-A Sulfur containing compound which functions as a bleach accereration agent FUJI PHOTO FILM CO., LTD. (JP) 1991-11-19 US disclosed
US-4966835-A HAVING A BLOCKED BLEACH ACCELERATOR CLEAVABLE DURING PROCESSING TO ALLOW FOR RAPID BLEACHING AND DESILVERING FUJI PHOTO FILM CO., LTD. (JP) 1990-10-30 US disclosed