SCHEMBL9770216

SCHEMBL9770216

CC(C)c1cc(=O)n(-c2ccccc2)n1C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.62
LMNA P02545 3/20 0.53
ADORA3 P0DMS8 1/20 0.53
CYP1A2 P05177 2/20 0.44
KDM4E B2RXH2 1/20 0.44
CYP2D6 P10635 1/20 0.44
POLB P06746 1/20 0.43
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
ALDH1A1 P00352 2/20 0.42
ALOX15 P16050 2/20 0.42
BCHE P06276 1/20 0.42
PTGS2 P35354 1/20 0.42
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
MAPT P10636 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
THRB P10828 1/20 0.40
TSHR P16473 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17034698 0.83 NAPRT (0.56) NAPRTLMNAADORA3CYP1A2KDM4E
Antipyrine SCHEMBL20452 0.77 NAPRT (1.00) NAPRTLMNAADORA3CYP1A2KDM4E
SCHEMBL4322718 0.76 NAPRT (0.61) NAPRTLMNAADORA3CYP1A2POLB
Antipyrine SCHEMBL18260589 0.76 NAPRT (0.96) NAPRTLMNAADORA3CYP1A2KDM4E
Antipyrine SCHEMBL8995343 0.76 NAPRT (0.96) NAPRTLMNAADORA3CYP1A2KDM4E
Antipyrine SCHEMBL7020007 0.76 NAPRT (0.96) NAPRTLMNAADORA3CYP1A2KDM4E
Antipyrine SCHEMBL8736656 0.76 NAPRT (0.96) NAPRTLMNAADORA3CYP1A2KDM4E
SCHEMBL7842787 0.76 NAPRT (0.65) NAPRTLMNAADORA3CYP1A2KDM4E
Antipyrine SCHEMBL28445203 0.76 NAPRT (0.96) NAPRTLMNAADORA3CYP1A2KDM4E
Antipyrine SCHEMBL9845605 0.76 NAPRT (0.96) NAPRTLMNAADORA3CYP1A2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118026938-B Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-06-28 CN claimed
CN-118026938-A Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-05-14 CN claimed
CN-118026938-B Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-06-28 CN disclosed
CN-118026938-A Pyrazolone ester compound and electrochemical synthesis method thereof 江西本草天工科技有限责任公司 2024-05-14 CN disclosed
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed
US-4918045-A SUPPORTS, MICROCAPSULES CONTAINING COLORLESS ELECTRON-DONATING COLOR FORMER AND SOLVENT, AND ELECTRON-ACCEPTING DEVELOPER FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
US-4888321-A SUBBING AND RECORDING LAYERS EACH CONTAINING HEAT FUSIBLE MATERIAL WITH DEFINED MELTING POINT FUJI PHOTO FILM CO., LTD. (JP) 1989-12-19 US disclosed
US-4876233-A NICKEL COMPOUNDS; COLORFASTNESS FUJI PHOTO FILM CO., LTD. (JP) 1989-10-24 US disclosed
US-4871713-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-10-03 US disclosed
US-4870048-A COLORFAST IMAGE, LIGHT RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1989-09-26 US disclosed
US-4839332-A AMINO-SUBSTITUTED FLUORENE AND ACID; DISCOLORATION INHIBITON, CHEMICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1989-06-13 US disclosed
US-4835133-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1989-05-30 US disclosed
US-4833118-A COLOR DEVELOPERS, SUBBING LAYERS, AROMATIC ESTERS OR CARBONATES FUJI PHOTO FILM CO., LTD. (JP) 1989-05-23 US disclosed
EP-0275203-A2 Heat-sensitive recording material containing color forming components FUJI PHOTO FILM CO., LTD. (JP) 1988-07-20 EP disclosed