Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770411 | 0.86 | BACE1 (0.60) | KDM4ECYP1A2BACE1ALOX15KMT2A | |
| SCHEMBL9770381 | 0.84 | KMT2A (0.50) | KDM4ECYP1A2BACE1ALOX15KMT2A | |
| SCHEMBL9770447 | 0.83 | BACE1 (0.57) | KDM4ECYP1A2BACE1KMT2ALMNA | |
| SCHEMBL9770415 | 0.83 | BACE1 (0.57) | KDM4ECYP1A2BACE1KMT2ALMNA | |
| SCHEMBL9770547 | 0.81 | CYP1A2 (0.59) | KDM4ECYP1A2BACE1KMT2ALMNA | |
| SCHEMBL13360698 | 0.81 | KDM4E (0.70) | KDM4ECYP1A2ALOX15KMT2ALMNA | |
| SCHEMBL9770387 | 0.80 | BACE1 (0.51) | KDM4ECYP1A2BACE1KMT2ALMNA | |
| SCHEMBL9770559 | 0.80 | BACE1 (0.51) | BACE1NPSR1MAPT | |
| SCHEMBL9480490 | 0.80 | BACE1 (0.80) | KDM4ECYP1A2BACE1KMT2ALMNA | |
| SCHEMBL9770521 | 0.78 | BACE1 (0.52) | CYP1A2BACE1KMT2AMEN1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |