Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770411 | 0.86 | BACE1 (0.60) | BACE1KMT2AMEN1GAACA1 | |
| SCHEMBL9770500 | 0.85 | KMT2A (0.45) | BACE1KMT2AMEN1GAAATM | |
| SCHEMBL9770410 | 0.84 | BACE1 (0.49) | BACE1KMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL9770447 | 0.83 | BACE1 (0.57) | BACE1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL9770237 | 0.83 | KDM4E (0.57) | BACE1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL9770547 | 0.81 | CYP1A2 (0.59) | BACE1KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL9480490 | 0.80 | BACE1 (0.80) | BACE1KMT2AMEN1LMNAMAPK1 | |
| SCHEMBL9770521 | 0.78 | BACE1 (0.52) | BACE1KMT2AMEN1GAACYP1A2 | |
| SCHEMBL9770529 | 0.78 | BACE1 (0.51) | BACE1KMT2ACA1CA2CA4 | |
| SCHEMBL9770387 | 0.77 | BACE1 (0.51) | BACE1KMT2AMEN1ATMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |