Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770436 | 0.80 | BACE1 (0.53) | BACE1 | |
| SCHEMBL9770237 | 0.80 | KDM4E (0.57) | BACE1MAPTNPSR1 | |
| SCHEMBL9770411 | 0.79 | BACE1 (0.60) | BACE1MAPT | |
| SCHEMBL9770447 | 0.77 | BACE1 (0.57) | BACE1MAPTHTTNPSR1 | |
| SCHEMBL9770415 | 0.77 | BACE1 (0.57) | BACE1 | |
| SCHEMBL9770387 | 0.77 | BACE1 (0.51) | BACE1MAPT | |
| SCHEMBL9770547 | 0.75 | CYP1A2 (0.59) | BACE1ABCB1MAPT | |
| SCHEMBL9690575 | 0.75 | TSHR (0.49) | ABCB1MAPTHTTNPSR1 | |
| SCHEMBL9480490 | 0.74 | BACE1 (0.80) | BACE1L3MBTL1 | |
| SCHEMBL10842173 | 0.74 | ADRB2 (0.68) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | claimed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | claimed |
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |