Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.31 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.31 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL448937 | 0.80 | MEN1 (0.50) | MAPK1MEN1KMT2A | |
| SCHEMBL14855632 | 0.72 | CYP2A6 (0.52) | MEN1KMT2A | |
| SCHEMBL2089857 | 0.71 | HPGD (0.46) | CYP3A4MAPK1TDP1 | |
| SCHEMBL1758628 | 0.71 | MEN1 (0.50) | MEN1KMT2A | |
| SCHEMBL227130 | 0.70 | CYP1A2 (0.44) | MAPK1TDP1MEN1KMT2A | |
| SCHEMBL5544097 | 0.70 | CYP3A4 (0.33) | CYP3A4MAPK1TDP1MEN1KMT2A | |
| SCHEMBL2094786 | 0.69 | HTR2A (0.41) | CYP3A4MAPK1TDP1AHRCXCR1 | |
| SCHEMBL7554632 | 0.69 | MAPT (0.41) | CYP3A4MAPK1TDP1AHRCXCR1 | |
| SCHEMBL2094784 | 0.69 | CYP3A4 (0.40) | CYP3A4MAPK1TDP1AHRCXCR1 | |
| SCHEMBL1758465 | 0.68 | PDK1 (0.44) | MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042591-A | PIGMENTS, DISPERSE DYES | SANDOZ LTD. (CH) | 1977-08-16 | — | — | US | claimed |
| US-5051346-A | Silver halide emulsion containing a coupler dispersed in oil droplets and another in an alkali aqueous solution; color films; improved photosensitivity, graininess, sharpness, reproduction | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1991-09-24 | — | — | US | disclosed |
| EP-0334362-A2 | Heat developable color light-sensitive material | Fuji Photo Film Co., Ltd. (JP) | 1989-09-27 | — | — | EP | disclosed |
| US-4053465-A | CYANOPHENYL-AZO-AMINOPHENYL DYESTUFFS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |
| US-4042591-A | PIGMENTS, DISPERSE DYES | SANDOZ LTD. (CH) | 1977-08-16 | — | — | US | disclosed |