Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227130 | 0.82 | CYP1A2 (0.44) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL9770282 | 0.80 | CYP3A4 (0.36) | MEN1KMT2AMAPK1 | |
| SCHEMBL2099071 | 0.79 | MAPT (0.51) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL3251079 | 0.78 | MEN1 (0.46) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL2094422 | 0.75 | RAF1 (0.42) | MEN1KMT2ALMNAHPGDKDM4E | |
| SCHEMBL2094076 | 0.75 | CYP1A2 (0.38) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL11463688 | 0.73 | L3MBTL1 (0.37) | LMNAMAPK1NPC1HPGDRAB9A | |
| SCHEMBL4159994 | 0.72 | MEN1 (0.52) | MEN1KMT2ALMNAMAPTMAPK1 | |
| SCHEMBL3076867 | 0.71 | ALDH1A1 (0.41) | MEN1KMT2ALMNAMAPTHPGD | |
| SCHEMBL560892 | 0.70 | MEN1 (0.50) | MEN1KMT2ALMNAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7825147-B2 | Inhibitors of phosphodiesterase type-IV | RANBAXY LABORATORIES LIMITED (IN) | 2010-11-02 | — | — | US | claimed |
| US-20080070864-A1 | Quinazolinone Modulators Of Nuclear Receptors | X-CEPTOR THERAPEUTICS, INC. (US) | 2008-03-20 | — | — | US | claimed |
| EP-1663999-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES, LTD. (IN) | 2006-06-07 | — | — | EP | claimed |
| EP-1521746-A1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X-Ceptor Therapeutics, Inc. (US) | 2005-04-13 | — | — | EP | claimed |
| US-20050075383-A1 | Inhibitors of phophodiesterase type-IV | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | US | claimed |
| WO-2005021515-A2 | INHIBITORS OF PHOSPHODIESTERASE TYPE-IV | RANBAXY LABORATORIES LIMITED (IN) | 2005-03-10 | — | — | WO | claimed |
| WO-2003076418-A1 | QUINAZOLINONE MODULATORS OF NUCLEAR RECEPTORS | X-CEPTOR THERAPEUTICS, INC. (US) | 2003-09-18 | — | — | WO | claimed |
| EP-1189891-A1 | TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF | LION Bioscience AG (DE) | 2002-03-27 | — | — | EP | claimed |
| US-6362342-B1 | BIOSYNTHESIS; DRUG LIBRARIES | LION BIOSCIENCE AG (DE) | 2002-03-26 | — | — | US | claimed |
| EP-0688775-B1 | Method for the purification of 23 -E isomers of 23-imino derivatives of LL-F28249 compounds | AMERICAN CYANAMID CO (US) | 2002-03-06 | — | — | EP | claimed |
| US-4916154-A | 23-Imino derivatives of LL-F28249 compounds | AMERICAN CYANAMID COMPANY (US) | 1990-04-10 | — | — | US | claimed |
| US-4886829-A | ANTHELMINTICS, NEMATICIDES, MITICIDES, INSECTICIDES; CROPS AND MAMMALS | AMERICAN CYANAMID COMPANY (US) | 1989-12-12 | — | — | US | claimed |
| US-4877888-A | INSECTICIDES, PARASITICIDES, NEMATICIDES, ACARICIDES | AMERICAN CYANAMID COMPANY (US) | 1989-10-31 | — | — | US | claimed |
| EP-0293549-A1 | 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds | AMERICAN CYANAMID COMPANY (US) | 1988-12-07 | — | — | EP | claimed |
| EP-0260536-A2 | 23-imino derivatives of 23-keto compounds useful as pesticides. | AMERICAN CYANAMID COMPANY (US) | 1988-03-23 | — | — | EP | claimed |
| EP-0260537-A1 | 13-Deoxy-23-oxo(keto) and 23-imino derivatives of 13-deoxy C-076-aglycone compounds | AMERICAN CYANAMID COMPANY (US) | 1988-03-23 | — | — | EP | claimed |
| EP-0259779-A1 | 23-Oxo (Keto) and 23-imino Derivatives of LL-F28249 Compounds | AMERICAN CYANAMID COMPANY (US) | 1988-03-16 | — | — | EP | claimed |
| US-4394158-A | PLANT GROWTH REGULATORS AND SAFENING AGENTS | CIBA-GEIGY CORPORATION (US) | 1983-07-19 | — | — | US | claimed |
| US-4347372-A | Benzoxazolyl-glyoxylonitrile-2-oxime ether derivatives | CIBA-GEIGY CORPORATION (US) | 1982-08-31 | — | — | US | claimed |
| US-4006163-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070864-A1 | Quinazolinone Modulators Of Nuclear Receptors | NR1H4, NR1H2, NR1H3 | MEN1 4424/4885KMT2A 3861/4885LMNA 3754/4885 |
| US-20050075383-A1 | Inhibitors of phophodiesterase type-IV | PDE7A, PDE4A, PDE4B | MEN1 4818/4885KMT2A 4537/4885LMNA 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.