SCHEMBL9770328

SCHEMBL9770328

CC1=NN(c2cc(Cl)ccc2Cl)C(=O)C1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.66
KMT2A Q03164 8/20 0.66
KDM4E B2RXH2 5/20 0.66
GAA P10253 4/20 0.66
ALDH1A1 P00352 6/20 0.62
MEN1 O00255 6/20 0.62
TDP1 Q9NUW8 4/20 0.62
LMNA P02545 3/20 0.62
HTT P42858 2/20 0.62
CASP6 P55212 2/20 0.56
POLB P06746 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
CYP1A2 P05177 1/20 0.49
CHRM2 P08172 1/20 0.49
CYP3A4 P08684 1/20 0.49
CHRM1 P11229 1/20 0.49
TSHR P16473 1/20 0.49
PTGS1 P23219 1/20 0.49
DRD3 P35462 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10596954 0.88 MAPT (0.62) MAPTKMT2AKDM4EGAAALDH1A1
SCHEMBL10435333 0.88 MAPT (0.67) MAPTKMT2AKDM4EGAAALDH1A1
SCHEMBL6757551 0.81 MAPT (0.48) MAPTKMT2AKDM4EGAAALDH1A1
SCHEMBL29851934 0.81 MAPT (0.60) MAPTKMT2AKDM4EGAAALDH1A1
SCHEMBL3407787 0.81 MAPT (0.60) MAPTKMT2AKDM4EGAAALDH1A1
SCHEMBL5464226 0.81 MAPT (0.43) MAPTKMT2AKDM4EGAAALDH1A1
SCHEMBL18267342 0.80 MAPT (0.81) MAPTKMT2AKDM4EGAAALDH1A1
SCHEMBL1260486 0.79 MAPT (1.00) MAPTKMT2AKDM4EGAAALDH1A1
SCHEMBL3528352 0.79 PDCD1 (0.45) MAPTKMT2AKDM4EGAAALDH1A1
SCHEMBL14559428 0.79 SHMT2 (0.43) MAPTKMT2AKDM4EGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5064895-A POLYARYLENE SULFIDE MOLDING COMPOUNDS AND THEIR USE AS AN ENCAPSULATING COMPOUND FOR ACTIVE AND PASSIVE ELECTRONIC COMPONENTS BAYER AKTIENGESELLSCHAFT (DE) 1991-11-12 US disclosed
US-5032674-A Polythioethers BAYER AKTIENGESELLSCHAFT (DE) 1991-07-16 US disclosed
US-5001220-A Pyrazolone substituted copolyarylene sulfide BAYER AG (DE) 1991-03-19 US disclosed
EP-0332966-A1 High-molecular, optionally branched-chain co-polyarylene sulphides, their production and their use BAYER AG (DE) 1989-09-20 EP disclosed
EP-0138749-B1 PROCESS FOR MASS DYEING SYNTHETIC POLYAMIDES CIBA-GEIGY AG (CH) 1989-08-23 EP disclosed
US-4527994-A Process for mass-coloring nylon with 1:2 chromium complex azo dye CIBA-GEIGY CORPORATION (US) 1985-07-09 US disclosed
EP-0138749-A2 Process for mass dyeing synthetic polyamides CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 US disclosed
US-3935182-A Water-soluble quaternary ammonium heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1976-01-27 US disclosed