Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | APP | P05067 | 7/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12756285 | 0.90 | MAPT (0.81) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL125079 | 0.85 | MAPT (0.74) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL5462610 | 0.83 | MAPT (0.72) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL1854311 | 0.83 | MAPT (0.70) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL4338431 | 0.83 | MAPT (0.70) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL4662959 | 0.83 | MAPT (0.70) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL11858486 | 0.83 | KMT2A (0.70) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL4325917 | 0.81 | MAPT (1.00) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL21597225 | 0.81 | MAPT (0.68) | MAPTKMT2AKDM4EGAAALDH1A1 | |
| SCHEMBL4662941 | 0.81 | MAPT (0.68) | MAPTKMT2AKDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024110326-A1 | USE OF YELLOW THERMOSTABLE METHINE DYES FOR DYEING PLASTICS | LANXESS DEUTSCHLAND GMBH (DE) | 2024-05-30 | — | — | WO | disclosed |
| CN-110003271-B | Process for producing aromatic compound | 住友化学株式会社 | 2022-05-03 | — | — | CN | disclosed |
| CN-113200993-A | Synthesis method of oxindole spirodihydrofuran compound | 浙江工业大学 | 2021-08-03 | — | — | CN | disclosed |
| US-11045796-B2 | Process for producing aromatic compound, and palladium complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20210128529-A1 | DRUG CONTAINING PYRAZOLONE DERIVATIVE | NOBELPHARMA CO., LTD. (JP) | 2021-05-06 | — | — | US | disclosed |
| CN-112118839-A | Pyrazolone derivative-containing drug | 耐贝医药株式会社 | 2020-12-22 | — | — | CN | disclosed |
| EP-3666270-A1 | DRUG CONTAINING PYRAZOLONE DERIVATIVE | Nobelpharma Co., Ltd. (JP) | 2020-06-17 | — | — | EP | disclosed |
| US-20180369799-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-12-27 | — | — | US | disclosed |
| EP-1793821-B1 | PYRAZOLONE COMPOUNDS FOR TREATING CEREBROVASCULAR DISORDERS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-10-31 | — | — | EP | disclosed |
| EP-3385270-A1 | METHOD FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX | Sumitomo Chemical Company, Ltd (JP) | 2018-10-10 | — | — | EP | disclosed |
| EP-1306131-A2 | Cross-Coupling catalyst comprising a cyclic nitrogen ligand and process using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-02 | — | — | EP | disclosed |
| US-RE35801-E | PYRAZOLONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0208874-B1 | PROPHYLACTIC AND THERAPEUTIC AGENT FOR CIRCULATORY DISORDERS | MITSUBISHI KASEI CORPORATION (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-4857542-A | INHIBITOR AGAINST LIPID PEROXIDATION | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1989-08-15 | — | — | US | disclosed |
| US-4822891-A | ANALYZING HYDROGEN PEROXIDE | FUJI PHOTO FILM CO., LTD. (JP) | 1989-04-18 | — | — | US | disclosed |
| US-4711963-A | 4-amino-2-methyl-3-phenyl-1-(2,4,6-trichlorophenyl)-3-pyrazolin-5-one | FUJI PHOTO FILM CO., LTD. (JP) | 1987-12-08 | — | — | US | disclosed |
| EP-0208874-A1 | Prophylactic and therapeutic agent for circulatory disorders | MITSUBISHI KASEI CORPORATION (JP) | 1987-01-21 | — | — | EP | disclosed |
| US-4527994-A | Process for mass-coloring nylon with 1:2 chromium complex azo dye | CIBA-GEIGY CORPORATION (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0138749-A2 | Process for mass dyeing synthetic polyamides | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-4160643-A | FOR POLYMERS OF ACRYLONITRILE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11045796-B2 | Process for producing aromatic compound, and palladium complex | DDT, DRD1, DRD2 | MAPT 4235/4885KMT2A 1175/4885KDM4E 969/4885 |
| US-20180369799-A1 | PROCESS FOR PRODUCING AROMATIC COMPOUND, AND PALLADIUM COMPLEX | DDT, DRD1, DRD2 | MAPT 4235/4885KMT2A 1175/4885KDM4E 969/4885 |
| US-20210128529-A1 | DRUG CONTAINING PYRAZOLONE DERIVATIVE | CYP11B2, CYP3A5, DPYD | MAPT 4271/4885KMT2A 1306/4885KDM4E 694/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.