SCHEMBL9770334

SCHEMBL9770334

OC(COCC(O)c1cccc2ccccc12)c1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2C9 P11712 2/20 0.48
ALDH1A1 P00352 1/20 0.48
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
TSHR P16473 2/20 0.44
NR2E1 Q9Y466 2/20 0.44
ADRA2A P08913 2/20 0.42
ADRA2B P18089 2/20 0.42
ADRA2C P18825 2/20 0.42
ADRA1D P25100 2/20 0.42
ADRA1A P35348 2/20 0.42
ADRA1B P35368 2/20 0.42
ACP3 P15309 1/20 0.41
AOC3 Q16853 1/20 0.41
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
SLC6A4 P31645 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8673517 0.93 CYP2C19 (0.46) CYP2C19CYP1A2CYP2C9ALDH1A1KMT2A
SCHEMBL8481171 0.88 KMT2A (0.43) CYP2C19CYP1A2CYP2C9ALDH1A1KMT2A
SCHEMBL8481811 0.87 HTR1B (0.46) CYP2C19CYP1A2CYP2C9ALDH1A1KMT2A
SCHEMBL8872829 0.83 HTR1B (0.50) ALDH1A1KMT2AKDM4EMEN1TSHR
SCHEMBL6327747 0.82 LMNA (0.49) CYP2C19CYP1A2CYP2C9ALDH1A1KMT2A
Hydrochloric Acid SCHEMBL8482513 0.82 HTR1B (0.49) ALDH1A1KMT2AKDM4EMEN1TSHR
SCHEMBL7931403 0.82 CNR1 (0.44) CYP2C9KMT2AKDM4ETSHRHTT
Hydrochloric Acid SCHEMBL8480337 0.82 SLC6A4 (0.49) TSHRSLC6A4
SCHEMBL29227182 0.82 ALDH1A1 (0.40) CYP2C19CYP1A2CYP2C9ALDH1A1KMT2A
SCHEMBL29227178 0.82 HSP90AA1 (0.40) CYP2C19CYP1A2CYP2C9ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4981836-A Recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-01 US disclosed