Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770485 | 0.87 | BACE1 (0.55) | BACE1NPC1RAB9APTGS1SLC6A2 | |
| SCHEMBL9770533 | 0.86 | BACE1 (0.51) | BACE1NPC1RAB9APTGS1SLC6A2 | |
| SCHEMBL9770364 | 0.83 | BACE1 (0.51) | BACE1NPC1RAB9AKCNH2PPARD | |
| SCHEMBL9770521 | 0.81 | BACE1 (0.52) | BACE1NPC1RAB9AADRB2ADRB3 | |
| SCHEMBL9770439 | 0.80 | BACE1 (0.60) | BACE1NPC1RAB9APTGS1SLC6A2 | |
| SCHEMBL9770524 | 0.78 | BACE1 (0.49) | BACE1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9770447 | 0.78 | BACE1 (0.57) | BACE1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL9770529 | 0.78 | BACE1 (0.51) | BACE1NPC1RAB9APTGS1SLC6A2 | |
| SCHEMBL9770483 | 0.77 | BACE1 (0.48) | BACE1NPC1RAB9AKCNH2KMT2A | |
| SCHEMBL9770570 | 0.77 | BACE1 (0.76) | BACE1NPC1RAB9APTGS1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |