Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770364 | 0.87 | BACE1 (0.51) | BACE1NPC1RAB9ATSHRCYP1A2 | |
| SCHEMBL9770384 | 0.87 | BACE1 (0.51) | BACE1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL9770521 | 0.85 | BACE1 (0.52) | BACE1NPC1RAB9AKMT2AHTT | |
| SCHEMBL9770447 | 0.84 | BACE1 (0.57) | BACE1NPC1RAB9AKMT2AHTT | |
| SCHEMBL9770455 | 0.80 | BACE1 (0.58) | BACE1NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9770529 | 0.79 | BACE1 (0.51) | BACE1NPC1RAB9AKMT2ATSHR | |
| SCHEMBL9770533 | 0.79 | BACE1 (0.51) | BACE1NPC1RAB9AKMT2AHTT | |
| SCHEMBL9770570 | 0.79 | BACE1 (0.76) | BACE1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL9770401 | 0.78 | BACE1 (0.67) | BACE1NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL9770439 | 0.78 | BACE1 (0.60) | BACE1NPC1RAB9AKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |