Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.76 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770149 | 0.92 | BACE1 (0.67) | BACE1PTGS1SLC6A2ADRB3ADRB2 | |
| SCHEMBL9770401 | 0.92 | BACE1 (0.67) | BACE1PTGS1SLC6A2NPC1RAB9A | |
| SCHEMBL9770369 | 0.92 | BACE1 (0.67) | BACE1PTGS1SLC6A2NPC1RAB9A | |
| SCHEMBL9770412 | 0.92 | BACE1 (0.67) | BACE1PTGS1SLC6A2NPC1RAB9A | |
| SCHEMBL9770562 | 0.92 | BACE1 (0.67) | BACE1PTGS1SLC6A2NPC1RAB9A | |
| SCHEMBL9480490 | 0.92 | BACE1 (0.80) | BACE1PTGS1SLC6A2NPC1RAB9A | |
| SCHEMBL9770465 | 0.90 | BACE1 (0.76) | BACE1PTGS1SLC6A2NPC1RAB9A | |
| SCHEMBL9770321 | 0.90 | BACE1 (0.76) | BACE1PTGS1SLC6A2NPC1RAB9A | |
| SCHEMBL9770444 | 0.89 | BACE1 (0.64) | BACE1PTGS1SLC6A2NPC1RAB9A | |
| SCHEMBL9770450 | 0.89 | BACE1 (0.63) | BACE1PTGS1SLC6A2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |