Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770524 | 0.90 | BACE1 (0.49) | CYP1A2CYP2D6BACE1SLC2A1KMT2A | |
| SCHEMBL9770483 | 0.86 | BACE1 (0.48) | CYP1A2CYP2D6BACE1SLC2A1KMT2A | |
| SCHEMBL9770533 | 0.84 | BACE1 (0.51) | CYP1A2CYP2D6BACE1KMT2AMEN1 | |
| SCHEMBL9770447 | 0.84 | BACE1 (0.57) | CYP1A2BACE1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9770364 | 0.84 | BACE1 (0.51) | CYP1A2CYP2D6BACE1NPC1RAB9A | |
| SCHEMBL9770401 | 0.81 | BACE1 (0.67) | CYP1A2BACE1LMNAALDH1A1NPC1 | |
| SCHEMBL9770511 | 0.81 | BACE1 (0.53) | BACE1KMT2ANPC1RAB9A | |
| SCHEMBL10920777 | 0.80 | CYP1A2 (0.68) | CYP1A2CYP2D6SLC2A1KMT2AMEN1 | |
| SCHEMBL9770424 | 0.80 | BACE1 (0.59) | CYP1A2BACE1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5825457 | 0.79 | L3MBTL1 (0.47) | CYP1A2KMT2AMEN1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | claimed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | claimed |
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |