Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | SOD1 | P00441 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770455 | 0.88 | BACE1 (0.58) | BACE1NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9770401 | 0.87 | BACE1 (0.67) | BACE1NPC1RAB9AKCNH2PTGS1 | |
| SCHEMBL9770570 | 0.85 | BACE1 (0.76) | BACE1NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9770364 | 0.84 | BACE1 (0.51) | BACE1NPC1RAB9AKCNH2PPARD | |
| SCHEMBL9770439 | 0.83 | BACE1 (0.60) | BACE1NPC1RAB9AKMT2AKCNH2 | |
| SCHEMBL9770396 | 0.83 | BACE1 (0.59) | BACE1NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9770395 | 0.83 | BACE1 (0.59) | BACE1NPC1RAB9AKMT2APTGS1 | |
| SCHEMBL9770483 | 0.81 | BACE1 (0.48) | BACE1NPC1RAB9AKMT2AKCNH2 | |
| SCHEMBL9770444 | 0.81 | BACE1 (0.64) | BACE1NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9480490 | 0.81 | BACE1 (0.80) | BACE1NPC1RAB9AKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |