Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA4 | P22748 | 3/20 | 0.46 |
| ▸ | CA7 | P43166 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770529 | 0.84 | BACE1 (0.51) | BACE1CA1CA2CA4CA7 | |
| SCHEMBL9770415 | 0.84 | BACE1 (0.57) | BACE1CA1CA2CA4CA7 | |
| SCHEMBL9770369 | 0.81 | BACE1 (0.67) | BACE1SMN1; SMN2HPGDMEN1MAPT | |
| SCHEMBL9770511 | 0.81 | BACE1 (0.53) | BACE1CA1CA2CA4CA7 | |
| SCHEMBL9770396 | 0.80 | BACE1 (0.59) | BACE1CA1CA2CA4CA7 | |
| SCHEMBL9770148 | 0.79 | BACE1 (0.58) | BACE1CA1CA2CA4CA7 | |
| SCHEMBL9770409 | 0.76 | CYP1A2 (0.51) | BACE1SMN1; SMN2LMNAMEN1MAPT | |
| SCHEMBL9770381 | 0.76 | KMT2A (0.50) | BACE1ALOX15SMN1; SMN2LMNAMEN1 | |
| SCHEMBL9770533 | 0.76 | BACE1 (0.51) | BACE1SMN1; SMN2HPGDMEN1HTT | |
| SCHEMBL9770500 | 0.75 | KMT2A (0.45) | BACE1CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | claimed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | claimed |
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0338587-A2 | Recording material | KAO CORPORATION (JP) | 1989-10-25 | — | — | EP | disclosed |