Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770371 | 0.88 | BACE1 (0.45) | BACE1NPC1RAB9ACASRWDR5 | |
| SCHEMBL9770536 | 0.88 | BACE1 (0.62) | BACE1NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9770424 | 0.88 | BACE1 (0.59) | BACE1NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9770148 | 0.84 | BACE1 (0.58) | BACE1RAB9AKMT2AHSD17B10TSHR | |
| SCHEMBL9770438 | 0.84 | TSHR (0.59) | BACE1CASRTSHRMAPK1HIF1A | |
| SCHEMBL9770402 | 0.84 | BACE1 (0.58) | BACE1KMT2ATSHRMAPK1HIF1A | |
| SCHEMBL9770401 | 0.83 | BACE1 (0.67) | BACE1NPC1RAB9ATSHRMAPK1 | |
| SCHEMBL9480490 | 0.83 | BACE1 (0.80) | BACE1NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9770389 | 0.83 | BACE1 (0.64) | BACE1KMT2AHSD17B10PRMT5WDR77 | |
| SCHEMBL9770232 | 0.83 | BACE1 (0.64) | BACE1KMT2AHSD17B10TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071822-A | Electron donating colorless dye, electron accepting derivative of 1-(4-hydroxyphenylthio)-3-oxy-2-propanol; heat sensitive, image stability | KAO CORPORATION (JP) | 1991-12-10 | — | — | US | disclosed |